Using patients' own skin cells to heal large deep wounds
Official title: Amplification of Autologous Epidermal Cells to Repair Large Area Deep Wounds
Run by First Affiliated Hospital of the Chinese People's Liberation Army Naval Medical University · NCT05882110 · Data updated 2026-11-12
This study is testing whether using a patient's own skin cells can help heal large deep burns more effectively than traditional skin grafts.
Quick facts
| Study type | Interventional |
|---|---|
| Sex | All |
| Enrollment | 100 (estimated) |
| Sponsor | First Affiliated Hospital of the Chinese People's Liberation Army Naval Medical University Academic / other |
| Locations | 1 site (Shanghai, Shanghai Municipality) |
| Status | Recruiting |
| Started | October 1, 2023 |
| Main results expected | October 31, 2026 |
| Study ends | December 31, 2026 |
| Registry record updated | April 11, 2025 |
| Trial ID | NCT05882110 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are patients with at least 30% total body surface area trauma requiring prolonged healing.
✕Probably not a fit
Patients with less than 30% body surface area trauma will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study focuses on the transplantation of autologous epidermal cells to treat large deep burns. It involves taking small pieces of a patient's skin, culturing and amplifying these cells in a lab, and then transplanting them back to the wound site to promote healing. The approach aims to overcome the limitations of traditional skin grafting methods, which often require multiple procedures and can lead to complications such as scarring. By significantly expanding the available skin cells, the study seeks to provide a more effective solution for patients with extensive skin damage.
Why it matters
Potential benefit: If successful, this approach could greatly enhance wound healing and improve the quality of life for patients with severe burns.
How similar studies have gone: While similar approaches in skin tissue engineering have shown promise, this specific method of amplifying epidermal cells for large deep wounds is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with a body surface trauma of 30% TBSA or more and a wound that requires at least 2 weeks to repair as assessed by the clinician Exclusion Criteria: * Patient body surface trauma area less than 30% TBSA
Where it's running
-
Yicheng Ma
Shanghai, Shanghai Municipality, China Recruiting
Study contacts
- Study coordinator: Yicheng Ma
- Email: 15185903573@163.com
- Phone: 15185903573
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.