Using patient's own blood to treat gum recession

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to address gum recession by utilizing a patient's own tissue from the roof of the mouth or an alternative method using their blood to create a membrane for treatment. Patients seeking corrective surgery for aesthetic concerns or sensitivity will be enrolled and randomly assigned to different treatment sites. An intraoral scanner will be used to measure pre-operative volume and will be repeated at each follow-up visit over the anticipated five-year duration of the study. The study employs a split-mouth design to compare the effectiveness of the two approaches.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Adults 18yrs or older
2. Need of MG-tx for 2 or more sites for root coverage RT I and II (Cairo classification)
3. Class A +/-
4. No class V restoration present

Exclusion Criteria:

1. Patients who do not consent to recommended therapy
2. Patients who smoke
3. Patients who will not be able to comply with follow up protocols
4. Those who self report that they are pregnant.

Where it's running

• Tufts University School of Dental Medicine
  Boston, Massachusetts, United States Recruiting

Study contacts

• Principal investigator: Tannaz Shapurian, DMD, MSc — Tufts University School of Dental Medicine
• Study coordinator: Tannaz Shapurian, DDM, MSc
• Email: Tannaz.shapurian@tufts.edu
• Phone: 617.636. 6741

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Root coverage using different restorative materials in Class V lesions

  This study tests whether using glass ionomer cement, resin composite, or no restoration before root coverage surgery helps people with gum recession and neck lesions

  Recruiting Adiyaman University · Adıyaman, Merkez · NCT07687654

• Volume-stable collagen matrix vs graft for multiple gingival recessions

  This study tests whether a volume-stable collagen matrix can cover exposed roots as well as a traditional graft, in adults with multiple gingival recessions.

  Recruiting University of Sao Paulo · Ribeirão Preto, São Paulo · NCT07613775

• Gingival recession and its effect on oral health-related quality of life

  This project will see how common gingival recession is and whether it affects oral health-related quality of life in adults aged 18–45 who visit a tertiary dental center in Haryana.

  Recruiting Postgraduate Institute of Dental Sciences Rohtak · Rohtak, Haryana · NCT07557277

• Comparing a new 3D tunneling technique with a modified coronally advanced tunnel plus connective tissue graft for treating multiple RT2 gingival recession.

  This trial will try a new 3D tunneling surgical technique versus a modified coronally advanced tunnel with connective tissue graft to improve root coverage in adults who have multiple RT2 gingival recessions.

  Recruiting Cairo University · Cairo, AlManial · NCT07526259

• Using 3D dental imaging to lower gum recession during aligner treatment

  This test tries to see if planning aligner treatment with 3D CBCT imaging instead of 2D images can reduce gum recession for adults undergoing dental arch expansion.

  Recruiting University of Liege · Liège, Liege · NCT07513792

• Gum recession in adults with and without prior orthodontic treatment

  We will test which patient and tooth factors increase the chance of gum recession in adults who have or have not had orthodontic treatment.

  Recruiting Universitaire Ziekenhuizen KU Leuven · Leuven · NCT07445555

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.