Using passive leg movement to assess vascular health in aging veterans
Passive Limb Movement: A Tool to Assess Vascular Health and Guide Rehabilitation
This study looks at how moving the legs without effort can help us understand blood vessel health in older veterans and find better ways to support their recovery and heart health.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 130 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | VA Office of Research and Development Federal |
| Locations | 1 site (Salt Lake City, Utah) |
| Trial ID | NCT03625349 on ClinicalTrials.gov |
What this trial studies
This observational study focuses on the relationship between passive limb movement and vascular health in an aging population, particularly U.S. veterans. It aims to assess endothelial function and nitric oxide bioavailability through non-invasive ultrasound Doppler measurements of blood flow in the common femoral artery. By understanding how arterial aging contributes to cardiovascular disease, the study seeks to identify potential methods for improving rehabilitation strategies for those with mobility limitations and cardiovascular dysfunction.
Who should consider this trial
Good fit: Ideal candidates include young healthy individuals without cardiovascular disease and patients referred for angiography.
Not a fit: Patients with poor kidney function or existing cardiovascular disease may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide a clinically accepted method for assessing vascular health, potentially improving rehabilitation outcomes for aging patients with cardiovascular disease.
How similar studies have performed: Other studies have shown promise in using non-invasive methods to assess vascular health, but this specific approach is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Young healthy subjects: No evidence of cardiovascular disease. * Patients undergoing angiography: Clinical referral for an angiography. Exclusion Criteria: * Young healthy subjects: Evidence of cardiovascular disease. * Patients undergoing angiography: Poor kidney function.
Where this trial is running
Salt Lake City, Utah
- VA Salt Lake City Health Care System, Salt Lake City, UT — Salt Lake City, Utah, United States (Recruiting)
Study contacts
- Principal investigator: Russell S. Richardson, PhD — VA Salt Lake City Health Care System, Salt Lake City, UT
- Study coordinator: Van R Reese, BS MS
- Email: van.reese@hsc.utah.edu
- Phone: (801) 582-1565
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.