Using ozone to enhance the effectiveness of dental sealants

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the application of ozone on first or second secondary molars before the placement of pits and fissure sealants. The goal is to determine if ozone, known for its bactericidal properties and ability to remineralize enamel, can prolong the effectiveness of sealants in preventing dental caries. Participants will undergo a procedure where ozone is applied to their teeth, followed by the sealing process. The study aims to assess the long-term benefits of this combined approach in dental care.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* first or second secondary molars to be sealed
* possibility to isolate with rubber dam both the teeth involved
* no clear signs of pigmentations
* good general health

Exclusion Criteria:

* latex allergy
* epilepsy or other severe neurological pathologies
* psychiatric disease
* excessive sensibility to electrical current
* severe asthma
* enamel disorders, such as amelogenesis imperfect, white spots, fluorosis or Molar Incisors Hypomineralization

Where it's running

• Institute for Maternal and Child Health - IRCCS Burlo Garofolo-
  Trieste, Trieste, Italy Recruiting

Study contacts

• Principal investigator: Maddalena Chermetz, DDS,MSc — IRCCS Burlo Garofolo
• Study coordinator: Milena Cadenaro, DDS,MSc,PhD
• Email: milena.cadenaro@burlo.trieste.it
• Phone: +390403785358

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.