Using ozone therapy to relieve pain after wisdom tooth extraction
Influence of Ozone Therapy on Postoperative Pain Relief in the Surgical Treatment of Lower Third Molars: Randomized Controlled Trial
NA · Azienda Ospedaliera Ordine Mauriziano di Torino · NCT05949476
This study is testing if ozone therapy can help reduce pain after having wisdom teeth removed compared to standard care.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 55 (estimated) |
| Ages | 18 Years to 30 Years |
| Sex | All |
| Sponsor | Azienda Ospedaliera Ordine Mauriziano di Torino (other) |
| Locations | 1 site (Torino) |
| Trial ID | NCT05949476 on ClinicalTrials.gov |
What this trial studies
This clinical trial investigates the effects of ozone therapy on postoperative pain relief in patients undergoing the extraction of lower third molars. It employs a split-mouth design where one side receives standard care while the other side is treated with ozone in both gaseous and gel forms. The primary goal is to assess pain levels seven days post-surgery, alongside secondary objectives that include evaluating mouth opening limitations, analgesic intake, and quality of life. The study aims to provide insights into the efficacy of ozone therapy in enhancing recovery after dental surgery.
Who should consider this trial
Good fit: Ideal candidates are individuals scheduled for lower third molar extraction without systemic diseases.
Not a fit: Patients with conditions such as hyperthyroidism, anemia, or those who are pregnant or breastfeeding may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly reduce postoperative pain and improve recovery for patients undergoing wisdom tooth extractions.
How similar studies have performed: While ozone therapy has been explored in various contexts, this specific application in dental surgery is relatively novel and has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Lower third molars included * Pell-Gregory Class II-B * Absence of systemic diseases Exclusion Criteria: * Hyperthyroidism; * G6PHD (glucose 6 phosphate dehydrogenase) deficiency; * Anemia * Myasthenia * Pregnancy and breastfeeding * Allergy to ozone * Local infections
Where this trial is running
Torino
- A.O. Ordine Mauriziano — Torino, Italy (RECRUITING)
Study contacts
- Study coordinator: Paolo Appendino, Dr.
- Email: pappendino@mauriziano.it
- Phone: +390115082222
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Extraction of the Lower Third Molars