Using ovarian platelet-rich plasma to improve IVF outcomes for women with diminished ovarian reserve

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective, double-blinded, randomized placebo-controlled trial investigates whether ovarian injections of platelet-rich plasma (oPRP) can enhance IVF outcomes in women aged 35 to 42 diagnosed with diminished ovarian reserve (DOR). Participants will undergo IVF with preimplantation genetic testing for aneuploidy (PGT-A) and will be randomly assigned to receive either oPRP or a placebo serum injection. The study will monitor participants through baseline assessments, ovulation induction, and subsequent embryo transfer cycles to evaluate the effectiveness of the treatment. The aim is to determine if oPRP can improve the chances of pregnancy and live birth in this population.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Clinical diagnosis of diminished ovarian reserve
* Clinical diagnosis of poor ovarian response
* Women age 35-42

Exclusion Criteria:

* Clinical diagnosis of premature ovarian failure
* Clinical diagnosis of menopause.
* Under 35 years of age
* Over 42 years of age

Where it's running

• Generation Next Fertility
  New York, New York, United States Recruiting

Study contacts

• Principal investigator: Jesse Hade, MD — Generation Next Fertility
• Study coordinator: Alicia Broussard, PhD
• Email: a.broussard@generationnextfertility.com
• Phone: 3174456958

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.