Using oral antibiotics to prevent anal fistulas after abscess drainage
Official title: Oral Antibiotics for Anal Abscess to Diminish the Developement of Perianal Fistula
Run by Germans Trias i Pujol Hospital · NCT03643198 · Data updated 2026-05-14
This study is no longer in our active list. It may have stopped recruiting or finished. The details below are as of 2026-05-14 and are kept for reference. Check ClinicalTrials.gov for its current status, or see similar studies below.
This study is testing if taking oral antibiotics after draining a perianal abscess can help prevent the formation of anal fistulas in patients.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 210 (estimated) |
| Sponsor | Germans Trias i Pujol Hospital Academic / other |
| Locations | 1 site (Barcelona) |
| Trial ID | NCT03643198 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adult patients over 18 years old with a clinical diagnosis of perianal abscess.
✕Probably not a fit
Patients with a history of previous perianal abscesses, inflammatory bowel disease, or existing anal fistulas will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This clinical trial investigates the effectiveness of oral antibiotics in preventing the development of anal fistulas following the drainage of perianal abscesses. It is a multicentre, double-blind, placebo-controlled trial that randomly assigns participants to receive either antibiotics or a placebo after their abscess has been treated. The study aims to clarify the role of antibiotic therapy in reducing the incidence of fistulas, which can significantly impact patients' quality of life. Participants will be monitored over a three-year period to assess outcomes.
Why it matters
Potential benefit: If successful, this study could significantly reduce the incidence of anal fistulas, improving patient outcomes and quality of life.
How similar studies have gone: Previous studies on this topic have shown inconclusive results, indicating that this approach is still under investigation.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adult patients over 18 years old * Clinical diagnosis of perianal abscess Exclusion Criteria: * Participants who have a history of previous perianal abscesses. * Inflammatory bowel disease * Patients who already have a perianal fistula * Patients with perianal cancer and / or pelvic radiotherapy * Perianal trauma * Immunodeficiency * Diabetes * Pregnancy or lactation * Valvular heart disease or prosthetic valve carriers * Spontaneous drainage * Previous use of antibiotics * Patients with a known allergy to Ciprofloxacin or Metronidazole.
Where it's running
-
David Parés
Barcelona, Spain Recruiting
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.