Using optical guidance for radiotherapy in head and neck cancer without a mask

Feasibility of Surface Optical Guidance to Replace the Restraint Mask for External Radiotherapy of Head and Neck Cancer

Not applicable Interventional Center Eugene Marquis · NCT06627075

This study is testing if using a special camera system to track patient movements during radiotherapy can help people with head and neck cancer get treated comfortably without the need for a tight mask.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment40 (estimated)
Ages18 Years and up
SexAll
SponsorCenter Eugene Marquis Academic / other
Drugs / interventionschemotherapy, immunotherapy
Locations1 site (Rennes, Brittany Region)
Trial IDNCT06627075 on ClinicalTrials.gov

What this trial studies

This clinical trial aims to evaluate the effectiveness of surface repositioning during radiotherapy sessions for patients with head and neck cancer, without the use of a restraining mask. Traditionally, masks are used to ensure consistent patient positioning, but they can cause discomfort and anxiety. The study will utilize optical surface camera systems to monitor patient movements and interrupt treatment if necessary, hypothesizing that this method can provide the same level of reproducibility as using a mask while enhancing patient comfort. The trial will include patients undergoing either palliative or curative treatment for oro-rhino-laryngeal cancer.

Who should consider this trial

Good fit: Ideal candidates are adults over 18 with oro-rhino-laryngeal cancer requiring radiotherapy.

Not a fit: Patients with uncontrollable movements or those under psychiatric care may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly improve patient comfort and quality of life during radiotherapy.

How similar studies have performed: While the use of optical surface guidance is becoming more common, this specific approach without a mask is relatively novel and has not been extensively tested.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients over 18 years of age
* Patients undergoing palliative or curative treatment for oro-rhino-laryngeal cancer
* Patients with an indication for radiotherapy treatment, with or without complementary treatment (chemotherapy, immunotherapy), with a number of sessions between 10 and 35
* Patients who have dated and signed an informed consent form

Exclusion Criteria:

* Patients with uncontrollable movements
* Patients under psychiatric care
* Patients who do not understand or read French
* Patients participating in an interventional study testing another medical intervention
* Patients under guardianship, curatorship, safeguard of justice or deprived of liberty
* Pregnant or breast-feeding women
* Patients without social security coverage

Where this trial is running

Rennes, Brittany Region

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Otorhinolaryngeal CancerRadiotherapyOptical surface guidance
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.