Using non-invasive spinal stimulation to improve ankle movement in spinal cord injury patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates the effectiveness of transcutaneous spinal cord stimulation (tSCS) in enhancing spinal circuitry adaptation for individuals with spinal cord injury (SCI). The study aims to determine the optimal parameters for tSCS and its priming effect during machine-assisted ankle movement training. It will evaluate both short-term and long-term clinical outcomes of combining tSCS with ankle movement training in participants with incomplete SCI, as well as healthy individuals. This approach seeks to provide a non-invasive alternative to traditional epidural spinal cord stimulation, which has limitations due to surgical requirements.

Why it matters

Who can join: the full rules

Health subjects:

Exclusion Criteria:

1. Musculoskeletal injuries on legs.
2. Osteoporosis.

SCI subjects:

Inclusion Criteria

1\. Participants with chronic spinal cord injury, with injury duration greater than one year.

Exclusion Criteria

1. Current musculoskeletal or joint injuries in the lower limbs.
2. History of central or peripheral neuromuscular diseases.
3. Presence of a pacemaker.
4. Current use of antispastic or antidepressant medications.
5. Current venous thromboembolism or osteoporosis.
6. Impairment of the soleus H-reflex arc.

Where it's running

• Chang Gung University
  Taoyuan, Taiwan Recruiting

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.