Using nitrous oxide canisters for pain relief during burn dressing changes

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This pilot trial aims to evaluate the effectiveness of disposable nitrous oxide canisters in providing pain control for adult burn patients during dressing changes. The study addresses the challenges of using traditional narcotics, which can be risky due to the narrow therapeutic window in burn patients. By comparing the effects of nitrous oxide inhalation to placebo canisters, the trial seeks to determine if this method can improve pain management without compromising patient safety or healing. The trial is designed as a randomized controlled trial to gather preliminary data on this approach.

Why it matters

Who can join: the full rules

Inclusion criteria

* adult burn patients admitted to the Health Sciences Centre
* total body surface area burned of 5-20%

Exclusion criteria

* admitted to intensive care unit
* unable to participate in the measurement outcomes (sedated, cognitively impaired, unable to understand English or visually impaired)
* medical condition that precludes using nitrous oxide (respiratory disease and significant cardiovascular disease 5).
* pregnant
* physically unable to hold the canister
* \<90% SaO2 on room air
* face burn
* pre-injury narcotics (relative exclusion)
* use of IV ketamine
* pre-existing lung injury

Where it's running

• University of Manitoba
  Winnipeg, Manitoba, Canada Recruiting

Study contacts

• Principal investigator: Sarvesh Logsetty — University of Manitoba
• Study coordinator: Sarvesh Logsetty, MD
• Email: logsetty@umanitoba.ca
• Phone: 2047878682

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.