Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Using neurofeedback to help reduce multiple drug use

Official title: Brain Mechanisms of Reducing Polysubstance Use Following a Novel Body-mind Intervention 2

Run by Arizona State University · NCT06324786 · Data updated 2026-11-12

This study is testing if using neurofeedback during body-mind training can help people who struggle with heavy drinking, cannabis use, and daily smoking reduce their drug use.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment35 (estimated)
SponsorArizona State University
Academic / other
Locations1 site (Phoenix, Arizona)
StatusRecruiting
StartedSeptember 1, 2023
Main results expectedAugust 31, 2027
Study endsAugust 31, 2027
Registry record updatedMay 4, 2026
Trial IDNCT06324786 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults aged 18 and older with a history of heavy episodic drinking, cannabis use, and daily cigarette smoking, without other psychiatric diagnoses.

Probably not a fit

Patients with psychiatric disorders other than substance use disorders or those currently using illicit drugs may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to evaluate the effectiveness of neurofeedback (NF) in enhancing integrative body-mind training (IBMT) to reduce polysubstance use. Participants will engage in IBMT while receiving real-time feedback on their brain activity, specifically targeting self-control networks. The study will include individuals with a history of heavy drinking, cannabis use, and daily cigarette smoking, who do not have other psychiatric diagnoses. The goal is to determine if this combined approach can lead to improved outcomes in managing substance use disorders.

Why it matters

Potential benefit: If successful, this approach could provide a novel non-pharmacological treatment option for individuals struggling with multiple substance use disorders.

How similar studies have gone: While the use of neurofeedback in substance use treatment is emerging, this specific combination of NF and IBMT is relatively novel and has not been extensively tested in prior studies.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* At least 18 years old
* Free of any psychiatric diagnoses or medication (besides a substance use disorder (SUD) to alcohol, tobacco, or cannabis)
* In the past month, at least 4 episodes of heavy episodic drinking; at least 3 occasions of cannabis use; and daily cigarette use for at least the past month
* Normal or corrected-to-normal vision
* Written informed consent
* No previous meditation or NF experiences

Exclusion Criteria:

* Any psychiatric diagnoses other than an SUD
* Medical disorder(s) that may affect the central nervous system; medications that affect the central and autonomic nervous system; or a positive pregnancy test result (females)
* Excluding cannabis, evidence of recent (past month) illicit drug use

Where it's running

  • YiYuan Tang
    Phoenix, Arizona, United States
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.