Using neural networks to analyze cleft palate shapes

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to develop a neural network that computes the three-dimensional geometry of the cleft palate using standard intraoral photographs and palatal casts from infants with cleft lip and palate deformities. By analyzing data collected from patients treated at the University Hospital Basel, the study seeks to reduce the treatment burden associated with cleft lip and palate. The neural network will allow for the reconstruction of palatal shapes from single images, potentially streamlining treatment planning and improving patient outcomes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients with cleft lip and palate malformation with available routinely performed plaster cast model from palatal impressions, intraoral scans from the palate and corresponding images of the cleft palate (1970 till 2025)

Exclusion Criteria:

* Existence of a documented rejection

Where it's running

• Mund-, Kiefer- und Gesichtschirurgie, Universitätsspital Basel
  Basel, Switzerland Recruiting

Study contacts

• Principal investigator: Andreas Müller, PD Dr. med. Dr. med. dent. Dr. — Mund-, Kiefer- und Gesichtschirurgie, Universitätsspital Basel
• Study coordinator: Benito Benitez, Dr. med. Dr. med. dent.
• Email: benito.benitez@usb.ch
• Phone: +41 61 556 52 85

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Effect of a cleft-adapted bottle with a unidirectional valve on milk intake in infants with cleft palate

  This study tests whether using a cleft-adapted bottle with a unidirectional valve helps infants with cleft palate take in more milk than a standard bottle.

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• Palatoplasty techniques using PRF and antibiotic-loaded PRF in cleft palate

  This trial tests whether adding autologous PRF or gentamicin-loaded PRF to primary palatoplasty helps kids with unilateral or bilateral cleft palate heal better and have fewer fistulas than standard surgery.

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• Opioid-free versus opioid-based anesthesia for children having cleft lip or palate repair

  This will test whether opioid-free anesthesia can control pain and reduce emergence agitation in children undergoing cleft lip or palate repairs.

  Recruiting University of Zagreb · Zagreb · NCT07557576

• Comparing pain relief methods after cleft palate surgery in children

  This study is testing whether short-acting or long-acting pain medications work better for managing pain in young children after cleft palate surgery.

  Recruiting Phase 4 Duke University · Durham, North Carolina · NCT06962306

• Furlow palatoplasty with buccal flap for speech in children with cleft palate

  This project compares two palate repair methods to see if Furlow palatoplasty with a buccal myomucosal flap leads to better speech than two-flap palatoplasty in children aged 3–5 with nonsyndromic cleft palate.

  Recruiting Fayoum University · Al Fayyum · NCT06856330

• Comparing two pain management techniques for children undergoing palate surgery

  This study is testing two different pain management techniques for kids aged 6-18 who are having palate surgery to see which one helps them feel less pain after the operation.

  Recruiting Medical University of South Carolina · Charleston, South Carolina · NCT06420336

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.