Clinical trial Recruiting at 1 site Interventional Ages 50 and up

Using negative pressure wound therapy after knee and hip surgeries

Official title: Routine Use of Negative Pressure Wound Therapy in Primary Hip and Knee Arthroplasties; a Randomized Controlled Trial

Run by Chinese University of Hong Kong · NCT06181097 · Data updated 2026-11-12

This study is testing if a special type of wound treatment can help people heal better and have fewer complications after knee or hip surgery compared to regular bandages.

Quick facts

Study typeInterventional
Ages50 Years and up
SexAll
Enrollment82 (estimated)
SponsorChinese University of Hong Kong
Academic / other
Locations1 site (Hong Kong)
StatusRecruiting
StartedDecember 11, 2023
Main results expectedDecember 10, 2025
Study endsDecember 10, 2026
Registry record updatedDecember 29, 2023
Trial IDNCT06181097 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are patients scheduled for total knee or total hip arthroplasty at Prince of Wales Hospital in Hong Kong.

Probably not a fit

Patients with conditions that impair wound healing, such as those on steroids or with a history of hypertrophic scarring, may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates the effectiveness of negative pressure wound therapy (NPWT) in reducing wound complications following total knee and total hip arthroplasty. A total of 40 patients will be randomly assigned to receive either NPWT or standard dressing after their surgeries. The study will monitor the incidence of wound complications over a 21-day period, as well as assess the aesthetic appearance and quality of the resulting scars. The goal is to determine if NPWT can improve healing outcomes compared to traditional methods.

Why it matters

Potential benefit: If successful, this approach could significantly reduce wound complications and improve scar quality for patients undergoing joint replacement surgeries.

How similar studies have gone: Previous studies have shown that negative pressure wound therapy can reduce complications in surgical wounds, suggesting a promising approach in this context.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients undergoing total knee or total hip arthroplasty at Prince of Wales Hospital, Hong Kong.

Exclusion Criteria:

* Patients using steroid, or other immune modulators that is known to affect wound healing, prior surgery to the knee or hip, skin condition such as eczema that would result in poor healing or widen scars, patients with a known significant history of hypertrophic scarring or keloid.

Where it's running

  • The Chinese University of Hong Kong
    Hong Kong, Hong Kong
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.