Using negative pressure therapy to improve healing in obese patients after breast reconstruction surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This trial investigates the effectiveness of negative pressure wound therapy (NPWT) in enhancing the healing of abdominal incisions in obese patients undergoing free flap breast reconstruction surgery. Participants are randomly assigned to receive either standard dressing or NPWT for a duration of 7 days post-surgery. The primary objective is to assess the impact of NPWT on wound dehiscence rates, with follow-up evaluations conducted at 2 weeks, 1 month, and 3 months to monitor long-term wound healing complications.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients undergoing a free abdominal flap, including a superficial inferior epigastric artery (SIEA), deep inferior epigastric artery perforator (DIEP), or muscle-sparing transverse rectus abdominus myocutaneous (MS-TRAM) flap for breast reconstruction.
* Patients are willing and able to give consent.
* Body mass index (BMI) greater than or equal to 30.0.

Exclusion Criteria:

* Patients who are unable to provide consent.
* Patients who are suspected or known to be pregnant.
* Known allergy to topical adhesives.

Where it's running

• M D Anderson Cancer Center
  Houston, Texas, United States Recruiting

Study contacts

• Principal investigator: Edward H Chang — M.D. Anderson Cancer Center
• Study coordinator: Edward H Chang
• Email: eichang@mdanderson.org
• Phone: 713-794-1247

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.