Using Nanopore Sequencing to Identify Pathogens in Eye Infections

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This pilot study assesses the feasibility of using the Oxford Nanopore MinION device to identify pathogens in vitrectomy samples from patients with endophthalmitis. During routine vitrectomy, vitreous samples and anterior chamber taps are collected and split for both standard microbial culture and nanopore sequencing. The results from nanopore sequencing are then compared to traditional culture methods to evaluate their effectiveness in pathogen identification. Clinical data regarding visual function and other features are also collected to provide a comprehensive overview of patient outcomes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Eyes of patients with endophthalmitis

Exclusion Criteria:

* No informed consent possible
* Participation in other studies

Where it's running

• Universitäts Augenklinik Graz
  Graz, Styria, Austria Recruiting

Study contacts

• Study coordinator: Michael Sommer, MD
• Email: michael.sommer@medunigraz.at
• Phone: 004331638531033

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.