Using myo-inositol during pregnancy to prevent gestational diabetes

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates the effects of myo-inositol, an insulin-like compound, on preventing gestational diabetes in pregnant women. It is a double-blind randomized controlled trial where participants will receive either myo-inositol or a placebo. The study aims to assess whether myo-inositol can improve insulin sensitivity and glycemic profiles in obese pregnant women. Participants will be monitored throughout their pregnancy to evaluate the outcomes related to gestational diabetes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

Singleton gestations

Women aged \> 18 years and \< 45 years

Recruited before 16 weeks gestation

Obese (pre-pregnancy BMI ≥ 30)

Receiving prenatal care at Tufts Medical Center

Planning to give birth at Tufts Medical Center

Can tolerate glucose tolerance test

Willing and able to wear CGM

Willing and able to sign informed consent

Exclusion Criteria:

Multiple gestation

Preexisting diabetes

Taking medications that impact body weight or metabolism (eg metformin)

Inability to tolerate glucose tolerance test

Adults unable to consent (cognitively impaired adults)

Wards of the state

Non-viable neonates

Neonates of uncertain viability

Where it's running

• Tufts Medical Center
  Boston, Massachusetts, United States Recruiting

Study contacts

• Study coordinator: Zeinab Kassem, MD
• Email: zeinab.kassem@tuftsmedicine.org
• Phone: 617-636-9897

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.