Using music to reduce apathy in Parkinson's Disease

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effects of music listening on apathy in patients with Parkinson's Disease (PD), a common non-motor symptom that significantly impacts quality of life. Apathy is characterized by a lack of motivation and emotional engagement, and current treatments have been largely ineffective. The research aims to explore how music can influence brain mechanisms associated with motivation and reward-seeking behaviors in PD patients. Participants will engage in music and podcast listening interventions to assess changes in apathy levels and overall functioning.

Why it matters

Who can join: the full rules

Inclusion Criteria:

\- Clinical diagnosis of Parkinson's Disease following MDS Parkinson's disease criteria

Exclusion Criteria:

* Participants with atypical Parkinsonism (eg. Progressive supranuclear palsy, multiple system atrophy, drug induced, etc.)
* Epilepsy
* Other neurological disease/complications (eg. myopathy, stroke, brain lesion, MS)
* Significant cognitive impairment (MoCa \<21)
* Moderate depression (Beck's Depression Inventory \>20)
* Severe/multiple head trauma(s)
* Participants with metal/medical implants, including any of the following: artificial heart valve, brain aneurysm clip, electrical stimulators, ear or eye implant, implanted drug infusion pump, coil, catheter, or filter in any blood vessel, orthopedic hardware such as artificial joint, plate, and/or screws, other metallic prostheses, shrapnel, bullets, or other metal fragments, surgery or tattoos, including tattooed eyeliner, in the last six weeks, cardiac pacemaker, wires or defibrillator, or ferromagnetic aneurysm clip)
* Participants who have gone through specific injuries/brain surgery (eg. an injury where a piece of metal lodged in the eye or orbit)

Where it's running

• Djavad Mowafghian Centre for Brain Health
  Vancouver, British Columbia, Canada Recruiting

Study contacts

• Study coordinator: Mikey Jose, B.Sc.
• Email: miguel.jose@ubc.ca
• Phone: (604) 822-3177

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• How physical activity might help people with Parkinson’s disease who have DBS-STN implants

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.