Using music during surgery to reduce inflammation in liver donors

Effect of Intraoperative Music on Inflammatory Response in Adult Living Donor Hepatectomy.

Not applicable Interventional Istinye University · NCT06166186

This study is testing whether playing music during liver donation surgery can help reduce inflammation and improve the overall experience for the donors.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment60 (estimated)
Ages18 Years to 70 Years
SexAll
SponsorIstinye University Academic / other
Locations1 site (Istanbul)
Trial IDNCT06166186 on ClinicalTrials.gov

What this trial studies

This study investigates the impact of intraoperative music on the inflammatory response during donor hepatectomy. It aims to determine whether music, as a non-pharmacological intervention, can alleviate pain, anxiety, and stress associated with surgical procedures. By comparing outcomes between patients who listen to music and those who do not, the study seeks to provide insights into the effectiveness of music in enhancing surgical experiences and recovery. The research is conducted at Istinye University Hospital in Istanbul.

Who should consider this trial

Good fit: Ideal candidates for this study are patients scheduled for donor hepatectomy who are classified as American Society of Anesthesiologists class 1 to 2.

Not a fit: Patients with a higher ASA classification or those on immunosuppressant or cytotoxic therapy may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could lead to improved recovery outcomes and reduced inflammatory responses for patients undergoing liver donation.

How similar studies have performed: Previous studies have shown that music can effectively reduce anxiety and pain in surgical settings, suggesting potential success for this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients undergoing donor hepatectomy
* American Society of Anesthesiologists class 1 to 2
* Ability to consent

Exclusion Criteria:

* American Society of Anesthesiologists greater than 2
* Documented or known sensitivity to any drug to be used in the study.
* Patient with immunosuppressant/ cytotoxic/ steroid therapy.
* not understand the aim and objectives of the study

Where this trial is running

Istanbul

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions TransplantationHepatectomyMusicStress Response
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.