Using muscle vibration to improve recovery after a stroke
Official title: The Effects of Muscle Vibration on the Development of Spasticity and Neuroplasticity in a Post-stroke Population (Acute and Subacute Phases): Randomized Controlled Trial
Run by Centre Hospitalier Universitaire Dijon · NCT05315726 · Data updated 2026-11-12
This study tests whether using muscle vibrations can help people recovering from a stroke feel better and regain movement more effectively.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 165 (estimated) |
| Sponsor | Centre Hospitalier Universitaire Dijon Academic / other |
| Locations | 2 sites (Chalon-sur-Saône and 1 other locations) |
| Status | Recruiting |
| Started | June 14, 2022 |
| Main results expected | July 2027 |
| Study ends | July 2027 |
| Registry record updated | February 9, 2026 |
| Trial ID | NCT05315726 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include adults who have experienced their first stroke within the last six weeks and have upper limb hemiparesis or hemiplegia.
✕Probably not a fit
Patients with significant pain during mobilization or those with other neurological conditions may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study investigates the effects of muscle vibration therapy on spasticity and neuroplasticity in post-stroke patients during the acute and sub-acute phases of recovery. By applying targeted muscle vibrations, the study aims to enhance functional recovery and reduce spasticity in patients who have experienced a stroke. The intervention includes the use of a dynamometer to deliver muscle vibrations, with a comparison to placebo vibrations. The study seeks to determine the effectiveness of this innovative approach in promoting rehabilitation outcomes.
Why it matters
Potential benefit: If successful, this therapy could significantly improve recovery outcomes and quality of life for post-stroke patients.
How similar studies have gone: While previous studies have shown promise for muscle vibration in chronic stroke rehabilitation, this approach in the acute and sub-acute phases is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: Phase 1: * Adult patient, * Medically stable on medical assessment, with no contraindications to stroke rehabilitation management management (no medical problems or acute intercurrent medical events), * Have had an ischemic and/or hemorrhagic stroke (\> 3 months post-stroke), impacting the motor skills of the upper limbs, * 1 ≤ MAS \< 4 on elbow or wrist flexors, * Having given oral consent. Phase 2: * Adult patient \> 18 years old, * Able to follow a rehabilitation program on medical opinion (no medical issues or acute intercurrent medical events), * First stroke ever \< 6 weeks, confirmed by imaging, * Hemiparesis or hemiplegia of the upper limb (FMA-UE score \< 48), particularly in the wrist and elbow flexors, * Requiring inpatient or outpatient hospitalization in a rehabilitation center, * Having given oral consent. Exclusion Criteria: * Phases 1 and 2: * Significant pain on mobilization of the wrist or elbow (VAS \> 5/10), * Presence of other neurological, muscular or osteoarticular conditions altering upper limb function, * Apparent wound, which may postpone inclusion, or very fragile skin, * Significant cognitive impairments: inability to understand simple instructions or give consent of any kind (not included if: LAST scores \< 5/7 in comprehension, and if YES/NO answers are unreliable), * Not covered by national health insurance, * Being pregnant or breastfeeding, * Being under guardianship or curatorship. * Person subject to a measure of legal protection
Where it's running
-
SSR Marguerite BOUCICAUT
Chalon-sur-Saône, France Recruiting -
Chu Dijon Bourgogne
Dijon, France Recruiting
Study contacts
- Study coordinator: Sophie JULLIAND
- Email: sophie.julliand@chu-dijon.fr
- Phone: 03.80.66.94.82
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.