Using MRI to Measure Blood Flow in the Eye
Official title: Arterial Spin Labeling MRI for Assessing Blood Perfusion in the Human Eye Repeatability Study and Clinical Application
Run by Cliniques universitaires Saint-Luc- Université Catholique de Louvain · NCT05724641 · Data updated 2026-11-12
This study is testing a new MRI method to see if it can safely measure blood flow in the eyes of patients with certain optic nerve conditions.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 70 (estimated) |
| Sponsor | Cliniques universitaires Saint-Luc- Université Catholique de Louvain Academic / other |
| Locations | 1 site (Brussels, Brussels Capital) |
| Status | Recruiting |
| Started | January 10, 2023 |
| Main results expected | June 30, 2026 |
| Study ends | June 30, 2026 |
| Registry record updated | May 16, 2025 |
| Trial ID | NCT05724641 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include individuals diagnosed with TAO optic neuropathy, inflammatory optic neuropathy, or ischemic optic neuropathy who do not have cardiovascular risk factors or other eye conditions.
✕Probably not a fit
Patients with contraindications to MRI, such as those with pacemakers or severe claustrophobia, may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study investigates the use of arterial spin labeling (ASL) MRI, a non-invasive imaging technique, to assess blood perfusion in the human eye. By measuring parameters such as regional blood flow and cerebral blood flow, the study aims to establish the reliability and specificity of the MRI protocol for evaluating retinal diseases. Participants will undergo MRI scans without the need for contrast agents, allowing for a safer assessment of their eye conditions. The study focuses on patients with specific optic neuropathies while ensuring they meet certain health criteria.
Why it matters
Potential benefit: If successful, this study could provide a reliable, non-invasive method for assessing blood flow in the eye, improving diagnosis and management of retinal diseases.
How similar studies have gone: While the use of ASL MRI is a relatively novel approach in this context, similar studies have shown promise in other areas of perfusion imaging.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion criteria: * Carrier of target pathologies: TAO optic neuropathy, inflammatory optic neuropathy, ischemic optic neuropathy. * no cardiovascular risk factors or other ophthalmological pathology * adhere to the study protocol after reading the patient information document * signe the informed consent form to participate in the study * do not have any contraindications to an MRI examination Exclusion criteria * Usual contraindications to MRI (Pacemaker, Metallic foreign body, Cochlear implant,…) * Severe claustrophobia
Where it's running
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Cliniques Universitaires Saint Luc
Brussels, Brussels Capital, Belgium Recruiting
Study contacts
- Principal investigator: Idil Günes-Tatar, MD — Cliniques universitaires Saint-Luc- Université Catholique de Louvain
- Study coordinator: Idil Günes-Tatar, MD
- Email: idil.gunes@saintluc.uclouvain.be
- Phone: +32.276442544
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.