Using MRI to evaluate lymphovascular space invasion in early cervical cancer
Magnetic Resonance Fingerprinting for Preoperative Evaluation of Lymphovascular Space Invasion in Early Stage Cervical Cancer
This study is testing if a new MRI technique can help doctors better understand lymphovascular space invasion in women with early-stage cervical cancer before their surgery.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 150 (estimated) |
| Ages | 18 Years and up |
| Sex | Female |
| Sponsor | Fondazione Policlinico Universitario Agostino Gemelli IRCCS Academic / other |
| Locations | 1 site (Roma) |
| Trial ID | NCT05808933 on ClinicalTrials.gov |
What this trial studies
This observational study aims to explore the effectiveness of Magnetic Resonance Fingerprinting (MRF) in the preoperative evaluation of lymphovascular space invasion in patients with early-stage cervical cancer. By utilizing advanced imaging techniques, the study seeks to improve the accuracy of pre-surgical assessments, potentially leading to better treatment planning. The study will include women diagnosed with FIGO stage IA-IIA cervical cancer who are scheduled for surgery, ensuring a focused approach to this specific patient population.
Who should consider this trial
Good fit: Ideal candidates for this study are women over 18 years old with biopsy-proven cervical cancer at FIGO stage IA-IIA who are planning to undergo surgery.
Not a fit: Patients with concurrent malignancies at other sites or a previous history of neoplasm may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance preoperative evaluations, leading to more tailored and effective treatment strategies for patients with early cervical cancer.
How similar studies have performed: While the use of Magnetic Resonance Fingerprinting is a relatively novel approach, similar imaging techniques have shown promise in other cancer evaluations, suggesting potential for success.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with biopsy-proven cervical cancer FIGO stage IA-IIA undergoing surgery; * Women aged \>18 years old; * Signed Informed Consent. Exclusion Criteria: * Concurrent malignancies at other sites; * Previous history of neoplasm; * Refusal to sign written informed consent
Where this trial is running
Roma
- Fondazione Policlinico Universitaro "A. Gemelli" IRCCS — Roma, Italy (Recruiting)
Study contacts
- Study coordinator: Benedetta B Gui, MD
- Email: benedetta.gui@policlinicogemelli.it
- Phone: 0630155464
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.