Using MRI to Diagnose Pancreatic Masses

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to utilize high order three-dimensional magnetic resonance elastography (3D-MRE) to non-invasively measure the stiffness of pancreatic lesions, particularly pancreatic ductal adenocarcinoma (PDAC). By assessing the mechanical properties of the extracellular matrix surrounding PDAC, the study seeks to identify prognostic factors that could aid in risk stratification and treatment decisions. The research focuses on patients with definitive histologic evidence of PDAC and aims to correlate MRE imaging biomarkers with patient outcomes. The goal is to enhance the understanding of tumor biology and improve clinical management of pancreatic cancer.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. granting of written informed consent
2. age ≥18 years
3. no history of extrapancreatic malignancy
4. no preoperative biliary drainage
5. definitive histologic evidence of PDAC in excisional biopsy
6. with no less than three months of postoperative mortality or six months of follow- up

Exclusion Criteria:

1. inability to re-review of tissue specimens
2. unacceptable estimates of MRE parameters, specifically invalid wave data during postprocessing, inconsistent breath-holdings, intolerable pain, and MRE hardware disconnection
3. tumor diameters \<1.0 cm
4. withdrawal/dropout during follow-up

Where it's running

• Shengjing hospital of china medical university
  Shenyang, Liaoning, China Recruiting

Study contacts

• Principal investigator: Yu Shi, MD.PhD. — Shengjing Hospital
• Study coordinator: Yu Shi, MD.PhD.
• Email: 18940259980@163.com
• Phone: 8618940259980

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Ketogenic Diet and Alcohol Intoxication: Can ketosis affect brain function and alcohol response

  This study tests whether a 4‑week ketogenic diet changes how the brain works and how the body handles alcohol in adults who drink regularly.

  Recruiting University of Pennsylvania · Philadelphia, Pennsylvania · NCT07602270

• How hormone and digestion functions and outcomes change after pancreas surgery

  This project will look back at medical records to see if different pancreatectomy methods, margin clearance, and how much pancreas is left affect hormone (endocrine) and digestion (exocrine) function and overall outcomes in adults who had pancreas surgery at our hospital.

  Recruiting National Taiwan University Hospital · Taipei, Taiwan · NCT07396662

• Slow stomach emptying after pancreatic surgery

  We will look back at adults who had pancreatic surgery to see if surgical technique, use of a gastrointestinal feeding tube, how cleanly the tumor was removed, or the size of the remaining pancreas affect delayed stomach emptying.

  Recruiting National Taiwan University Hospital · Taipei, Taiwn · NCT07382791

• Carbon ion radiotherapy for frail people with pancreatic cancer

  This trial will try carbon ion radiotherapy as a treatment for people with non-metastatic pancreatic cancer who are too frail for surgery or standard chemotherapy.

  Recruiting Phase 2 Yonsei University · Seoul · NCT07257523

• Using MRI to speed diagnosis and care for adults with acute stroke in the emergency room

  We will test whether a streamlined MRI protocol helps doctors diagnose and treat adults with acute stroke faster in the emergency department.

  Recruiting Tanta University · Tanta, El-Gharbia · NCT07138768

• Following memory decline in Alzheimer disease

  This project will use 7T MRI, EEG, blood and stool samples, and memory tests to see if they can track memory decline in people over 55 with Alzheimer's disease or mild cognitive impairment.

  Recruiting Norwegian University of Science and Technology · Trondheim, Trønderlag · NCT07118137

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.