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Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Using MRI to develop a virtual biopsy for glioma grading

Official title: Virtual Biopsy Development to Identify Patient's Glioma Grade at the CHU of Poitiers Using Magnetic Resonance Imaging

Run by Poitiers University Hospital · NCT04313140 · Data updated 2026-11-12

This study is testing a new way to use MRI scans to see if we can tell the grade of brain tumors called gliomas without needing to do a surgery.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment500 (estimated)
SponsorPoitiers University Hospital
Academic / other
Locations1 site (Poitiers)
StatusRecruiting
StartedFebruary 22, 2021
Main results expectedFebruary 2029
Study endsFebruary 2029
Registry record updatedMay 8, 2026
Trial IDNCT04313140 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are adults aged 18 and older with suspected gliomas who have prior imaging available.

Probably not a fit

Patients who are unable to undergo MRI examinations or those with legal protections, such as minors or individuals under guardianship, may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to develop a virtual biopsy technique that utilizes magnetic resonance imaging (MRI) to accurately identify the grade of gliomas, which are tumors of the central nervous system. Currently, the only definitive way to determine tumor grade is through anatomical biopsy, which can be invasive. By leveraging artificial intelligence algorithms, this approach seeks to provide a non-invasive alternative for assessing tumor characteristics based on prior imaging. The goal is to enhance clinical decision-making and treatment planning for patients with suspected gliomas.

Why it matters

Potential benefit: If successful, this approach could provide a less invasive method for glioma grading, improving patient comfort and potentially leading to more timely and appropriate treatments.

How similar studies have gone: While the use of MRI and artificial intelligence in tumor assessment is an emerging field, this specific approach to glioma grading through virtual biopsy is relatively novel and has not been extensively tested in prior studies.

Who can join: the full rules

Show full inclusion / exclusion criteria 
Inclusion Criteria:

* Age≥ 18 years,
* Patient with suspected glioma with prior imaging
* Subject free, with legal protection guardianship or curatorship;
* Enrollment in the French Social Security system;
* Informed consent signed by the patient

Exclusion Criteria:

* Any contraindication to an MRI examination
* Legal protection, namely minors, persons deprived of their liberty by a judicial or administrative decision, persons residing in a health or social establishment, adults under legal protection and finally patients in emergency situations
* Pregnant or lactating women, women of childbearing age who do not have effective contraception

Where it's running

  • CHU De Poitiers
    Poitiers, France     Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
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Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.