Using MRI to detect placenta adhesion issues in pregnant women

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to evaluate the effectiveness of quantitative MRI techniques in diagnosing Placenta Adhesion Abnormalities (PAA) in pregnant women between 30 and 38 weeks of gestation. By measuring specific MRI parameters related to placental perfusion and oxygenation, the study seeks to improve the detection rates of PAA compared to standard ultrasound methods. The research will involve participants who are at risk for PAA, such as those with low-lying or covering placentas. The MRI will be performed without the use of gadolinium-based contrast agents to ensure safety for the mother and fetus.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Pregnant participant between 30 and 38 weeks of gestation,
* Age ≥18 years old,
* Participant who completed the preliminary medical examination,
* Participant who has received full information about the organization of the research and has signed her informed consent.
* Participant planning to give birth at CHRU of Nancy
* Participant presenting risk factors for PAA : low-lying or covering placenta or in front of the uterine scar.

Exclusion Criteria:

* Multiple pregnancy,
* Participant presenting at least one contraindication or restriction to performing an MRI as described in the protocol, in accordance with the current recommendations,
* Participant unable to understand or follow study procedure,
* Person referred to in Articles L. 1121-6 to L. 1121-8, L1122-2 and L. 1122-1-2 of the Public Health Code.

Where it's running

• Centre Hospitalier Régional Universitaire de Nancy
  Vandœuvre-lès-Nancy, France Recruiting

Study contacts

• Study coordinator: Charline BERTHOLDT, MI
• Email: c.bertholdt@chru-nancy.fr
• Phone: +33 3 83 34 43 12

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.