Using MRI technology to improve cancer radiotherapy

Magnetic Resonance-Guided Adaptive Radiotherapy (MRgART) Using an Integrated Magnetic Resonance Linear Accelerator (MRL)

Observational University Health Network, Toronto · NCT04135794

This study is testing whether using MRI scans during radiotherapy can help people with cancer get better treatment and improve their quality of life.

Quick facts

Study typeObservational
Enrollment500 (estimated)
Ages18 Years and up
SexAll
SponsorUniversity Health Network, Toronto Academic / other
Locations1 site (Toronto, Ontario)
Trial IDNCT04135794 on ClinicalTrials.gov

What this trial studies

This study aims to enhance patient outcomes by utilizing Magnetic Resonance-guided adaptive radiotherapy (MRgART) with an Integrated Magnetic Resonance Linear Accelerator (MRL). Participants receiving radiotherapy will undergo additional MR scans during their treatment planning to allow for more precise targeting of their cancer. They will also complete quality of life questionnaires to assess the impact of this approach. The study focuses on understanding the benefits of MR-guided techniques in cancer treatment.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18 and older diagnosed with cancer who are scheduled to receive MR-guided adaptive radiotherapy.

Not a fit: Patients under 18 years old will not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could lead to more effective and personalized cancer treatment, improving patient outcomes.

How similar studies have performed: Other studies have shown promise with MR-guided radiotherapy approaches, indicating potential for success in this area.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients 18 years or older with a diagnosis of cancer, regardless of clinical site or stage
* Planned to receive a course of MR-guided adaptive RT using the MRL
* Ability to provide informed consent

Exclusion Criteria:

* Patients under 18 years old

Where this trial is running

Toronto, Ontario

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions CancerMRL
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.