Using MRI and radiomics to detect Brucella spondylitis

Radiomics Analysis Based on MRI to Detect Brucella Spondylitis

This study is testing if advanced MRI techniques can help doctors better diagnose Brucella spondylitis in patients with this infectious spinal disease.

Quick facts

• Study type: Observational
• Enrollment: 100 (estimated)
• Ages: 18 Years to 70 Years
• Sex: All
• Sponsor: The Affiliated Hospital of Inner Mongolia Medical University (other)
• Locations: 1 site (Hohhot, Inner Mongolia)
• Trial ID: NCT06220500 on ClinicalTrials.gov

What this trial studies

This observational study aims to improve the diagnosis of Brucella spondylitis, an infectious spinal disease, by utilizing advanced MRI techniques and radiomics analysis. The study will involve 100 patients diagnosed with Brucella spondylitis at the Affiliated Hospital of Inner Mongolia Medical University, where clinical data and MRI scans will be collected. The investigators will segment affected vertebral bodies and extract radiomics features to develop predictive models using machine learning techniques. The goal is to enhance diagnostic accuracy and provide better insights into the disease's pathophysiology.

Who should consider this trial

Good fit: Ideal candidates for this study are adults aged 18-70 who have been diagnosed with brucellosis and exhibit symptoms of brucella spondylitis.

Not a fit: Patients with serious comorbidities, a history of malignant tumors of the vertebral body, or contraindications to MRI may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to more accurate and non-invasive diagnostic methods for Brucella spondylitis, improving patient outcomes.

How similar studies have performed: While the use of radiomics in MRI for diagnosing various conditions is gaining traction, this specific application for Brucella spondylitis is relatively novel and has not been extensively tested in prior studies.

Eligibility criteria

Inclusion Criteria:

1. Outpatients/Inpatients
2. Age 18-70 years
3. Meet diagnostic criteria for brucellosis
4. Meet symptoms of brucellosis spondylitis
5. Voluntarily sign an informed consent form
6. Can cooperate with MRI examination

Exclusion Criteria:

1. Patients with serious diseases of other systems
2. History of malignant tumors of the vertebral body
3. History of tuberculosis
4. Contraindications to magnetic resonance imaging

Where this trial is running

Hohhot, Inner Mongolia

• Affiliated Hospital of Inner Mongolia Medical University — Hohhot, Inner Mongolia, China (RECRUITING)

Study contacts

• Study coordinator: Peng fei Qiao, MD

Conditions: Brucella Spondylitis, Radiomics, MRI