Using MR Fingerprinting to analyze vestibular schwannomas before treatment
MR-Fingerprinting for the Prediction of the Response of Vestibular Schwannomas to Gamma Knife Radiosurgery
This study is testing if a special MRI technique can help doctors understand how vestibular schwannomas respond to Gamma Knife treatment in patients with these tumors.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 50 (estimated) |
| Ages | 18 Years to 90 Years |
| Sex | All |
| Sponsor | Medical University of Vienna Academic / other |
| Locations | 1 site (Vienna) |
| Trial ID | NCT04851925 on ClinicalTrials.gov |
What this trial studies
This observational study involves performing MR Fingerprinting (MRF) on patients with vestibular schwannomas who are scheduled for Gamma Knife radiosurgery. A total of fifty patients with tumors measuring at least 1cm will be included, and their tumor responses to the radiosurgery will be monitored through MRI follow-ups. The primary goal is to identify patterns in the MRF data that correlate with different responses to the treatment, such as tumor control, growth, or cystic transformation post-surgery.
Who should consider this trial
Good fit: Ideal candidates for this study are patients with vestibular schwannomas that are 1cm or larger and are planning to undergo Gamma Knife radiosurgery.
Not a fit: Patients with vestibular schwannomas smaller than 1cm or those receiving treatments other than Gamma Knife radiosurgery will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance the understanding of how vestibular schwannomas respond to radiosurgery, potentially leading to improved treatment strategies.
How similar studies have performed: While the approach of using MR Fingerprinting is innovative, similar studies have not been widely reported, making this a novel investigation.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: Planned Gamma Knife radiosurgery for vestibular schwannoma of minimum 1cm in size - Exclusion Criteria: Vestibular Schwannoma of less than 1cm in size. Other a priori treatment than Gamma Knife radiosurgery -
Where this trial is running
Vienna
- Medical University of Vienna — Vienna, Austria (Recruiting)
Study contacts
- Principal investigator: Josa Frischer, MD — Medical University of Vienna
- Study coordinator: Dorian Hirschmann, MD
- Email: dorian.hirschmann@meduniwien.ac.at
- Phone: +4314040025780
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.