Using motivational interviewing to promote safe drug use and reduce overdose
Efficacy and Implementation Considerations for a Peer-led Motivational Interviewing Intervention to Promote Uptake of Drug Checking Services and Safe Drug Use Behaviors to Reduce Overdose
This study is testing a new approach called MI-CHANCE to see if it can help people who use drugs in San Diego stay safer and reduce the chances of overdose.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 588 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University of California, San Diego Academic / other |
| Locations | 1 site (San Diego, California) |
| Trial ID | NCT06855836 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effectiveness of a motivational interviewing intervention called MI-CHANCE to increase the use of drug checking services and promote safer drug use behaviors among people who use drugs in San Diego County. A total of 588 participants will be recruited and randomly assigned to either receive MI-CHANCE or standard education on flu and hepatitis A. The intervention aims to reduce the rates of both fatal and non-fatal overdoses over a 30-month period while examining factors that influence the effectiveness of the intervention. Participants will be followed up semi-annually to assess outcomes and adherence to safer drug use practices.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals aged 18 and older who have used illicit opiates or methamphetamine within the past week and reside in San Diego County.
Not a fit: Patients who do not use illicit opiates or methamphetamine or those who have previously utilized the CheckSD drug checking service may not benefit from this study.
Why it matters
Potential benefit: If successful, this intervention could significantly reduce overdose rates and improve health outcomes for people who use drugs.
How similar studies have performed: While motivational interviewing has been used in various health interventions, this specific approach to increase drug checking service uptake is novel and has not been rigorously evaluated in this context.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: A total of 588 PWUD participants will be recruited for the proposed study (MI-CHANCE). To be eligible to participate in this study, an individual must meet all of the following criteria: 1. Provision of signed and dated informed consent form 2. Stated willingness to comply with all study procedures and availability for the duration of the study 3. Be aged ≥18 years at time of recruitment 4. Must have used illicit opiates (e.g., heroin, fentanyl) and/or methamphetamine ≤1 week prior to recruitment date 5. Live in San Diego County with no plans to permanently move over the next 30 months 6. Have not previously used the CheckSD drug checking service 7. Enrolled into ongoing prospective cohort study La Frontera (the border) (existing or new participants) Enrollment will be capped so that \<25% of the sample reports only using methamphetamine to ensure that the sample is comprised primarily of people who use opiates who are at greatest risk of OD. Recruitment will be done through targeted sampling at hotspots as well as homeless encampments, shelters and outreach through social media. Exclusion Criteria: An individual who meets any of the following criteria will be excluded from participation in this study: 1. Not being able to provide a signed and dated informed consent form 2. Not willing to comply with all study procedures and availability for the duration of the study 3. Currently enrolled in another randomized controlled trial 4. Not having used illicit opiates (e.g., heroin, fentanyl), methamphetamine ≤1 week prior to recruitment date 5. Having used CheckSD (i.e. drug testing with TS+FTIR) 6. Participated in the MI-CHANCE pilot
Where this trial is running
San Diego, California
- MI CHANCE - Park Blvd — San Diego, California, United States (Recruiting)
Study contacts
- Study coordinator: Steffanie Strathdee, PhD
- Email: sstrathdee@health.ucsd.edu
- Phone: 858-822-1952
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.