Using morphine with bupivacaine for pain relief after inguinal hernia surgery
Intrathecal Non-preservative-free Morphine With Bupivacaine Versus Intrathecal Bupivacaine Alone for Analgesia in Unilateral Inguinal Hernia Repair Surgeries: A Randomized Controlled Clinical Trial.
PHASE3 · Cairo University · NCT06319859
This study is testing if adding morphine to bupivacaine can help people aged 18-65 feel less pain after inguinal hernia surgery compared to using bupivacaine alone.
Quick facts
| Phase | PHASE3 |
|---|---|
| Study type | Interventional |
| Enrollment | 50 (estimated) |
| Ages | 18 Years to 65 Years |
| Sex | All |
| Sponsor | Cairo University (other) |
| Locations | 1 site (Cairo) |
| Trial ID | NCT06319859 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effectiveness and safety of intrathecal non-preservative-free morphine combined with bupivacaine compared to bupivacaine alone for managing postoperative pain in patients undergoing unilateral inguinal hernia repair surgeries. The trial aims to determine if the addition of morphine can provide superior analgesia. Patients aged 18-65 with ASA I and II classifications will be recruited, while those with contraindications to spinal anesthesia or significant comorbidities will be excluded.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18-65 who are classified as ASA I or II and are scheduled for unilateral inguinal hernia surgery.
Not a fit: Patients with contraindications to spinal anesthesia, significant comorbidities, or allergies to local anesthetics may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could lead to improved pain management and recovery outcomes for patients undergoing inguinal hernia repair.
How similar studies have performed: Previous studies have shown promising results with similar intrathecal analgesic approaches, suggesting potential for success in this trial.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients aged 18-65 years old. * Both genders. * ASA I and II class. Exclusion Criteria: * Patient refusal. * Known local anesthetic (LA) allergy. * Skin lesions or infections at the site of needle insertion. * Contraindications to spinal anesthesia. * Failure of spinal anesthesia. * ASA III and VI class. * Central or peripheral neuropathies. * Severe respiratory or cardiac diseases.
Where this trial is running
Cairo
- Kasr Alaini hospital — Cairo, Egypt (RECRUITING)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Pain, Postoperative