Using Monocyte Distribution Width to Diagnose Sepsis in Patients with Other Health Issues

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to evaluate the effectiveness of Monocyte Distribution Width (MDW) as an early biomarker for diagnosing sepsis in patients with comorbidities such as renal failure, heart failure, and COPD. The study focuses on patients admitted to the emergency department for decompensation related to these conditions, where timely diagnosis is critical due to the high mortality rates associated with sepsis. By measuring MDW, the researchers hope to improve diagnostic accuracy and facilitate prompt treatment initiation, addressing the challenges posed by nonspecific symptoms in complex cases.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients aged over 18 years admitted to the emergency department for decompensation of congestive heart failure or renal failure, or exacerbation of COPD.

Exclusion Criteria:

* Patients who received antibiotic treatment in the past 7 days, pregnant women, children, non-consenting patients, patients with a history of malignant hematologic disease, polytransfused patients or those who recently received a transfusion, and patients whose MDW was not reported due to ineffective monocyte counting.

Where it's running

• Sahloul University Hospital
  Sousse, Tunisia Recruiting

Study contacts

• Study coordinator: Boukef Riadh Professor
• Email: riadboukef@gmail.com
• Phone: +216 98676745

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.