Using mixed reality to locate lung nodules before surgery
Application of Mixed Reality Technique for Percutaneous Lung Nodule Localization: A Prospective, Randomized, Controlled Trial
This study is testing if using mixed reality technology can help doctors find lung nodules more accurately before surgery in patients needing treatment for lung cancer.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 74 (estimated) |
| Ages | 18 Years to 80 Years |
| Sex | All |
| Sponsor | Shanghai Chest Hospital Academic / other |
| Locations | 1 site (Shanghai, Shanghai) |
| Trial ID | NCT05715996 on ClinicalTrials.gov |
What this trial studies
This clinical trial explores the use of mixed reality technology to improve the localization of solitary pulmonary nodules prior to surgical intervention. By integrating augmented reality into the preoperative process, the study aims to enhance the accuracy of lung nodule localization compared to traditional CT-guided methods. The trial will involve patients who require sub-lobectomy for lung cancer, assessing the effectiveness and efficiency of this innovative approach. Participants will be randomized to receive either the mixed reality-guided localization or the standard method.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 and older with solitary pulmonary nodules measuring 2 cm or less, who require localization for sub-lobectomy.
Not a fit: Patients with multiple lung nodules or those whose nodules are located in the scapular region may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could lead to more precise surgical interventions and improved outcomes for patients with lung cancer.
How similar studies have performed: While the use of augmented reality in surgical settings is emerging, this specific application for lung nodule localization is relatively novel and has not been extensively tested in prior studies.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Male or female ≥ 18years of age; 2. There was no distant metastasis in preoperative clinical evaluation; 3. The attending physician evaluated and confirmed the need for lung nodule localization and sub-lobectomy; 4. Target lung nodule diameter ≤ 2cm 5. The inner edge of the target node is at least 2 cm from the pulmonary artery or pulmonary vein 6. preoperative ECOG physical state score 0/1; 7. Volunteer to participate in the study and sign the informed consent form. Exclusion Criteria: 1. More than two lung nodules need to be removed at the same time. 2. The target node is located in the scapular region. Because percutaneous localization is obstructed by the scapula, percutaneous localization of pulmonary nodules is not suitable for such patients. 3. The patient has uncontrollable mental illness and cannot make subjective assessment. 4. After being selected, severe complications (unable to tolerate surgery or anesthesia) occurred before operation are not suitable or the treatment plan of the study cannot be implemented as planned; 5. After being selected, the patient's condition changes and needs to be changed from elective surgery to emergency surgery after being confirmed by the competent doctor; 6. At any stage after entering the study, the patient voluntarily requests to withdraw or discontinue treatment due to personal reasons.
Where this trial is running
Shanghai, Shanghai
- Zuodong Song — Shanghai, Shanghai, China (Recruiting)
Study contacts
- Study coordinator: Xinghua Cheng, MD
- Email: chengxinghua_001@163.com
- Phone: +8617701681215
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.