Using Misoprostol to Prevent Respiratory Issues in Newborns During Elective Cesarean Sections

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the effectiveness of administering Misoprostol before elective cesarean sections in pregnant women under 38 weeks gestation to reduce neonatal respiratory morbidity. Given the high incidence of respiratory distress syndrome in newborns delivered via cesarean, the research aims to determine if Misoprostol can mitigate these risks. The study will include women with singleton pregnancies and no major anomalies, while excluding those with certain obstetric disorders or contraindications to Misoprostol. The findings could provide valuable insights into improving neonatal outcomes in cesarean deliveries.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Women with indication for elective caesarean section.
* Age less than 35 years old.
* Gestational age less than 38 weeks.
* Gestational age will be confirmed by certain LMP or reliable early ultrasound measurement of crown-rump length.
* Singleton pregnancy with no major anomalies

Exclusion Criteria:

* Any obstetric disorders as preeclampsia and diabetes.
* Fetus with oligohydramnios, intrauterine growth restriction.
* Any contraindications to misoprostol like those with previous allergic reaction or hypersensitivity to prostaglandin hemorrhagic disorders, and severe anemia.
* History of more than or equal 2 previous caesarean section.

Where it's running

• Kafr El-sheikh University Hospital
  Kafr Ash Shaykh, Egypt, Egypt Recruiting

Study contacts

• Study coordinator: Merna Ashraf Ahmed farid, M.B.B.C.H
• Email: mernaashraf2551996@gmail.com
• Phone: 01093030236

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.