Using mirror therapy and electrical stimulation to improve movement in stroke patients

Effect of Mirror Therapy with Cutaneous Electrical Sensory Stimulation on Lower Limb Motor Functions in People with Stroke: a Single-blinded Randomized Controlled Trial

Not applicable Interventional The Hong Kong Polytechnic University · NCT03622879

This study is testing if combining mirror therapy with electrical stimulation can help stroke patients improve their movement and walking ability better than using either treatment alone.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment100 (estimated)
Ages55 Years to 85 Years
SexAll
SponsorThe Hong Kong Polytechnic University Academic / other
Locations1 site (Hong Kong)
Trial IDNCT03622879 on ClinicalTrials.gov

What this trial studies

This study evaluates the effectiveness of combining mirror therapy with transcutaneous electrical nerve stimulation (TENS) to enhance lower limb motor functions in individuals who have experienced a stroke. Participants will engage in task-oriented training while receiving these therapies, with the hypothesis that this combination will yield better results than either therapy alone or a control group. The approach aims to leverage visual feedback and electrical stimulation to improve motor function and walking ability by increasing cortical activity in the brain. The study will assess the outcomes over a defined period to determine the efficacy of this innovative rehabilitation method.

Who should consider this trial

Good fit: Ideal candidates are individuals who have had a single stroke within the last 6 to 36 months and can perform certain physical tasks independently.

Not a fit: Patients with additional medical conditions, severe visual deficits, or cognitive impairments may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly improve motor function and walking ability in stroke patients, enhancing their quality of life.

How similar studies have performed: While the combination of mirror therapy and TENS is a novel approach, similar studies have shown promise in improving rehabilitation outcomes for stroke patients.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. have had a single stroke with ischemic brain injury or intracerebral haemorrhage diagnosed by magnetic resonance imaging or computed tomography within the previous 6 to 36 months;
2. have at least 5 degrees of active ankle dorsiflexion in the antigravity position;
3. are able to walk 10 m independently with or without a walking aid;
4. are able to score 6 or higher out of 10 on the abbreviated mental test;
5. have no unilateral neglect, hemianopia or apraxia;
6. have no skin allergy (e.g. redness or itchiness to the electrical stimulation pads) to electrical stimulation or electrodes; and
7. are able to follow instructions and give informed consent.

Exclusion Criteria:

1. have any additional medical, cardiovascular or orthopaedic condition that would hinder proper treatment or assessment;
2. have visual deficits that may hinder them from benefiting from the mirror visual feedback;
3. have receptive dysphasia; or
4. are involved in drug studies or other clinical trials.

Where this trial is running

Hong Kong

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions StrokeMirror therapyTranscutaneous Electric Nerve StimulationRehabilitation
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.