Using minced skin grafts to improve healing of donor sites after skin grafting
Evaluation of the Use of Minced Skin Grafts for Promoting Donor Site Wound Healing After Split-Thickness Skin Grafting: A Prospective Half-side Comparative Study
This study tests if using small pieces of skin from the donor site can help wounds heal faster and better after skin grafting.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 20 (estimated) |
| Ages | 12 Years to 60 Years |
| Sex | All |
| Sponsor | Sohag University Academic / other |
| Locations | 1 site (Sohag) |
| Trial ID | NCT06488612 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effectiveness of using minced skin grafts from the donor site to enhance wound healing after split-thickness skin grafting (STSG). It aims to compare the healing duration, scar quality, and cosmetic outcomes of donor sites treated with minced grafts versus those without. The study addresses the often-overlooked management of donor site morbidity, which can include complications like delayed healing and scarring. By utilizing leftover skin graft material, the research seeks to optimize donor site recovery and minimize associated complications.
Who should consider this trial
Good fit: Ideal candidates are patients aged 12 to 60 years who are scheduled for split-thickness skin grafting.
Not a fit: Patients under 12 or over 60 years, those with a history of hypertrophic scarring or keloids, and individuals with uncontrolled comorbidities may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly reduce healing time and improve cosmetic outcomes for patients undergoing skin grafting.
How similar studies have performed: While there have been some studies on the use of residual skin grafts, this specific approach of using minced grafts for donor site healing is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * All patients undergoing split-thickness skin grafting, between 12 - 60 years of age. Exclusion Criteria: * Patients under the age of 12 years or above 60 years. * Patients with a known tendency for hypertrophic scarring/keloids * Pregnancy * Co-morbid factors such as uncontrolled diabetes, ischemic heart disease, renal failure or Collagen vascular disease.
Where this trial is running
Sohag
- Plastic surgery department, Faculty of medicine, Sohag university — Sohag, Egypt (Recruiting)
Study contacts
- Study coordinator: Mohamed Abd Elmawla Mohamed, Resident plastic surgeon
- Email: mohamed_abdelmageed@med.sohag.edu.eg
- Phone: +0201221953861
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.