Using microRNAs to diagnose Non-Hodgkin's Lymphoma
Biochemical Role of Circulating microRNAs Expression as Diagnostic Markers for Non-Hodgkin's Lymphoma Patients
Sohag University · NCT05921812
This study is testing if certain tiny molecules in the blood can help doctors better diagnose people who have just been diagnosed with Non-Hodgkin's lymphoma.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 70 (estimated) |
| Ages | 18 Years to 75 Years |
| Sex | All |
| Sponsor | Sohag University (other) |
| Locations | 1 site (Sohag) |
| Trial ID | NCT05921812 on ClinicalTrials.gov |
What this trial studies
This observational study aims to investigate the role of circulating microRNAs as potential diagnostic markers for patients with Non-Hodgkin's lymphoma. It will include patients who have been newly diagnosed with this type of cancer and are treatment-naïve. The study will utilize real-time PCR to analyze the expression of microRNAs in the blood of participants. By identifying specific microRNA patterns, the study seeks to improve diagnostic accuracy for Non-Hodgkin's lymphoma.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 18 to 75 who have newly diagnosed, histologically confirmed Non-Hodgkin's lymphoma and have not yet received any anti-neoplastic treatment.
Not a fit: Patients who are younger than 18 or older than 75, or those with other malignancies, will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to more accurate and earlier diagnoses of Non-Hodgkin's lymphoma, improving patient outcomes.
How similar studies have performed: While the use of microRNAs as diagnostic markers is a growing field, this specific approach in Non-Hodgkin's lymphoma is relatively novel and has not been extensively tested in prior studies.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. This study will include patients who have newly diagnosed, histo-pathologically proved Non-Hodgkin's lymphoma. 2. Age from 18 to 75 years old. 3. anti-neoplastic treatment naïve patients. 4. No associated other malignancies (neither Synchronous nor metachronous) than Non-Hodgkin's lymphoma. Exclusion Criteria: 1. children below 18 years old or elderly people more than 75 years old 2. patients not newly diagnosed with non-Hodgkin's lymphoma 3. presence of any associated other malignancies than non-Hodgkin's lymphoma
Where this trial is running
Sohag
- Sohag University — Sohag, Egypt (RECRUITING)
Study contacts
- Study coordinator: shrouk M Galal, demonstrator
- Email: shroukmostafa@med.sohag.edu.eg
- Phone: 01117449592
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Non-Hodgkin Lymphoma