Using microdoses of ICG for bowel perfusion assessment during surgery
Microdosing ICG for Serial Colonic Perfusion Study During Surgery
NA · University of California, San Diego · NCT06254833
This study is testing whether a smaller dose of a dye called indocyanine green can help doctors better see blood flow in the intestines during surgery compared to a regular dose.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 20 (estimated) |
| Ages | 18 Years to 80 Years |
| Sex | All |
| Sponsor | University of California, San Diego (other) |
| Locations | 1 site (La Jolla, California) |
| Trial ID | NCT06254833 on ClinicalTrials.gov |
What this trial studies
This study investigates the effects of microdosing indocyanine green (ICG) compared to regular dosing for assessing bowel perfusion during intestinal resection surgeries. Patients will be randomly assigned to receive either 7.5mg or 0.75mg of ICG, with the goal of determining the optimal dosing for effective perfusion imaging. The study utilizes advanced imaging equipment to enhance the accuracy of perfusion assessments, potentially leading to improved surgical outcomes.
Who should consider this trial
Good fit: Ideal candidates are patients undergoing intestinal resection surgery.
Not a fit: Patients who are pregnant or have renal insufficiency may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could lead to better surgical outcomes by optimizing bowel perfusion assessment during surgeries.
How similar studies have performed: Other studies have shown promise in using ICG for perfusion assessment, but the microdosing approach is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * all patient undergoing intestinal resection surgery Exclusion Criteria: * pregnancy, renal insufficiency
Where this trial is running
La Jolla, California
- UC San Diego — La Jolla, California, United States (RECRUITING)
Study contacts
- Study coordinator: Shanglei Liu
- Email: jtt005@health.ucsd.edu
- Phone: (858)249-1837
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Perfusion, Complications