Using micro connective tissue grafts to treat multiple gum recession defects
Official title: Tunnel Surgery Combined With a Micro Connective Tissue Graft for the Treatment of Multiple Adjacent Gingival Recession Defects: a Multi-center Randomized Controlled Clinical Trial.
Run by Göteborg University · NCT06030947 · Data updated 2026-11-12
This study is testing whether a new type of small gum graft can help people with multiple gum recession areas heal better than the traditional graft method.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 60 Years |
| Sex | All |
| Enrollment | 30 (estimated) |
| Sponsor | Göteborg University Academic / other |
| Locations | 1 site (Dubai) |
| Status | Recruiting |
| Started | March 1, 2025 |
| Main results expected | January 1, 2026 |
| Study ends | August 1, 2026 |
| Registry record updated | March 13, 2025 |
| Trial ID | NCT06030947 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are systemically healthy adults aged 18 and older with 4 to 6 adjacent gingival recessions of at least 2 mm in depth.
✕Probably not a fit
Patients who smoke, have uncontrolled medical conditions, or a history of previous root coverage procedures may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This project aims to evaluate the one-year outcomes of treating multiple adjacent gingival recession defects (MAGRD) using a modified coronally advanced tunnel technique (MCAT). Participants will be divided into two groups, one receiving conventional connective tissue grafts (CTG) and the other receiving micro-CTGs. The study will assess the effectiveness and predictability of micro-CTGs compared to traditional methods, focusing on root coverage and patient outcomes. The research addresses the challenge of limited donor tissue when treating multiple defects.
Why it matters
Potential benefit: If successful, this approach could provide a less invasive and more effective treatment option for patients with multiple gum recession defects.
How similar studies have gone: While traditional connective tissue grafts have shown favorable results, the use of micro-CTGs is a novel approach that has not been extensively tested in similar studies.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * age ≥18 years, * systemically healthy, * presenting with a minimum of 4 and a maximum of 6 adjacent RT1/RT2 recessions, located in the maxilla or mandible with an apico-coronal extension (i.e. recession depth) of ≥2 mm, * Full-Mouth Plaque Score (FMPS) \<20%, * Full-Mouth Bleeding Score (FMBS) \<20%. Exclusion Criteria: * pregnancy or lactation, * tobacco smoking, * uncontrolled medical condition, * medication that can affect gingival conditions. * thick phenotype, * severe tooth malpositioning, * uncorrected trauma from toothbrushing, * a previous history of root coverage procedures * the presence of furcation defects.
Where it's running
-
Confident Dubai Palm
Dubai, United Arab Emirates Recruiting
Study contacts
- Study coordinator: Olivier Carcuac, DDS, PhD
- Email: olivier.carcuac@gu.se
- Phone: 556275575
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Palatal Wound Healing After Free Gingival Graft in Diabetic Patients
This study tests palatal wound healing after a free gingival graft in adults with and without diabetes to see if diabetes affects healing and what factors are linked to outcomes.
-
Oral Mucosa Healing After Gum Recession Treatment in Diabetic People
This study tests how gingival recession treatment heals in people with diabetes compared with people without diabetes.
-
Theravex Oral and Theravex Tissue Care Plus to improve healing after mucogingival surgery
We will test if applying Theravex Tissue Care Plus during a modified free gingival graft and rinsing with Theravex Oral afterward helps adults with lower-front gum recession heal faster and get better root coverage than a saline placebo.
-
Healing the palatal donor site after a free gingival graft using a topical steroid
This trial will test whether applying topical triamcinolone acetonide to the palatal donor site helps adults having free gingival graft surgery heal faster and with less pain than a standard collagen sponge.
-
3D comparison of soft tissue changes after modified versus conventional free gingival grafts
This trial will try a modified free gingival graft against a conventional free gingival graft in adults with localized lower-front gum recession to see which better preserves soft tissue thickness and volume.
-
TCAF versus MTUN with soft tissue grafts for a single gum recession in the lower premolar area
This compares whether a tunneled coronally advanced flap (TCAF) or a modified tunnel (MTUN), each combined with a connective tissue graft, gives better root coverage for adults with a single gum recession in the lower premolar area.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.