Using medicinal herbs to help the immune system fight COVID-19

The Trial Uses Medicinal Herbs to Direct T Cells to Engulf the COVID-19 Virus and Protect the Organs Well

This study is testing if using medicinal herbs can help boost the immune system in people with COVID-19 to prevent serious complications.

Quick facts

• Phase: Phase1; Phase2
• Study type: Interventional
• Enrollment: 100 (estimated)
• Sex: All
• Sponsor: All Natural Medicine Clinic, LLC (Academic / other)
• Locations: 1 site (Rockville, Maryland)
• Trial ID: NCT04790240 on ClinicalTrials.gov

What this trial studies

This clinical trial investigates the use of medicinal herbs to enhance the immune response in patients diagnosed with COVID-19. The study aims to address the issue of cytokine storms, which occur when the immune system overreacts to the virus, leading to severe organ damage. Participants will receive treatments involving various herbal interventions alongside standard care, with evaluations conducted throughout the study to assess their immune function and overall health. The trial includes both Phase 1 and Phase 2 assessments to determine safety and efficacy.

Who should consider this trial

Good fit: Ideal candidates include individuals aged 10-70 who have been diagnosed with COVID-19 within the past 1-20 days.

Not a fit: Patients who have previously recovered from COVID-19 and no longer show active infection will not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could provide a novel treatment option that enhances the immune response against COVID-19 and reduces the severity of the disease.

How similar studies have performed: While the use of medicinal herbs in treating viral infections is a novel approach, similar studies exploring immune modulation have shown promise in other contexts.

Eligibility criteria

Inclusion Criteria:

A subject will be eligible for inclusion in this study if any of the following criteria apply:

* Individuals diagnosed with COVID-19 virus infection in the past 1-20 days must submit the proved metrics of COVID-19 virus marks positive during the registration;
* The age of participants is between 10-70 years old;
* The participants are received or not received conventional medication treatment, and continuing the treatment patients, could be enrolled in this clinical study;
* This clinical study is not restricted to gender, age, sex, race, and nationality;
* The participants must have reports of CBC, C3, C4, IgM, IgG, CD4/CD8, and lungs' images ready before the clinical study;
* The Participants must repeat the evaluation experiment during and at the end of the clinical study.

Exclusion Criteria:

A subject will not be eligible for inclusion in this study if any of the following criteria apply:

* Individuals with a prior COVID-19 virus infection that no longer shows up from COVID-19 testing;
* Children who are younger than 10-year-old, cannot control themselves to take the medical herbs on time;
* Elders whose age beyond 70-year-old, with severe underline illness;
* COVID-19 virus-infected patients who do not feel willing to take medical herbs;
* Patients diagnosed with COVID-19 virus infection cannot consistently finish the treatment courses for a specific reason;
* Patients diagnosed with COVID-19 virus infection but do not willing to share their information with the public;
* Current or past participation within a specified timeframe in another clinical trial, as warranted by this intervention's administration;
* Severe patients, when there have insufficient normal cells, can be adjusted, with pre-list diseases life-threatening.

Where this trial is running

Rockville, Maryland

• All Natural Medicine Clinic, LLC — Rockville, Maryland, United States (Recruiting)

Study contacts

• Principal investigator: Wanzhu Hou, CMD,MD(CN) — All Natural Medicine Clinic, LLC
• Study coordinator: Wanzhu Hou, CMD, MD(CN)

Conditions Covid19 Virus Infection; Medicinal Herbs; Virus; COVID-19; Coronavirus Disease 2019; Infections; Inflammation; Immunity