Using magnetocardiography to identify heart ischemia in patients with suspected NSTE-ACS

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This multi-center observational study aims to evaluate the effectiveness of magnetocardiography (MCG) in the rapid and accurate identification of ischemia in patients experiencing chest pain suspected of non-ST-elevation acute coronary syndrome (NSTE-ACS). The study utilizes the spin-exchange relaxation-free (SERF) principle to detect weak magnetic fields generated by the heart, which can provide more diagnostic information than traditional electrical methods. By optimizing and validating MCG models, the study seeks to establish a faster and more reliable strategy for detecting coronary ischemia compared to routine diagnostic techniques. Participants will undergo MCG assessments as part of their evaluation for potential coronary angiography or coronary CTA.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Age 18 years or older;
2. Patients with symptoms of myocardial ischemia such as angina who are suspected to NSTE-ACS and proposed to undergo CAG or coronary CTA;
3. Signed informed consent.

Exclusion Criteria:

1. Patients with ST-elevation myocardial infarction (STEMI);
2. Patients with Non-ischemic dilated cardiomyopathy, or hypertrophic cardiomyopathy, or moderate or severe valvular disease;
3. Patients with Hemodynamic instability (systolic blood pressure\<90 mmHg, or who requires vasoactive drugs), or patients with tachyarrhythmia, Ⅱ degree atrioventricular block and above that have not returned to normal;
4. Patients who have severe renal abnormality with eGFR \<30 ml/min, or patients who are on dialysis;
5. Patients with malignant tumors with predicted survival of less than 1 year;
6. Pregnant or breastfeeding women;
7. Patients who are unable to enter the MCG device, who are unable to perform MCG examination due to interference from metal implants or other reasons, or who are deemed by the investigators to be unsuitable for enrollment.

Where it's running

• Qilu Hospital of Shandong University
  Jinan, Shandong, China Recruiting

Study contacts

• Principal investigator: Yuguo Chen, Professor — Qliu Hospital of Shandong University
• Study coordinator: Jiaojiao Pang, Doctor
• Email: jiaojiaopang@126.com
• Phone: 0086-0531-82165398

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.