Using magnetic stimulation to improve arm function after stroke
A Randomized, Controlled, Patient- and Assessor- Blinded, Exploratory Clinical Trial to Search the Stimulation Site for Repetitive Transcranial Magnetic Stimulation (rTMS) That Improves Upper Extremity Function After Stroke
NA · Bundang CHA Hospital · NCT06322797
This study is testing if a special type of magnetic stimulation can help improve arm function in people who are recovering from a stroke.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 15 (estimated) |
| Ages | 20 Years and up |
| Sex | All |
| Sponsor | Bundang CHA Hospital (other) |
| Locations | 1 site (Seongnam) |
| Trial ID | NCT06322797 on ClinicalTrials.gov |
What this trial studies
This clinical trial evaluates the safety and effectiveness of repetitive transcranial magnetic stimulation (rTMS) to enhance upper extremity function in patients who have experienced a stroke. It employs a randomized, controlled, and blind methodology, utilizing functional magnetic resonance imaging (fMRI) to identify specific brain regions for targeted stimulation. The study focuses on individuals who are at least three months post-stroke, a period often associated with slow recovery. By combining rTMS with fMRI insights, the trial aims to establish a more effective rehabilitation approach for stroke survivors.
Who should consider this trial
Good fit: Ideal candidates are adults over 20 years old who are at least three months post-stroke with a National Institutes of Health Stroke Scale (NIHSS) score between 1 and 20.
Not a fit: Patients with severe medical conditions or those unable to provide informed consent may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved rehabilitation techniques for stroke patients, enhancing their ability to regain arm function.
How similar studies have performed: While some studies have explored rTMS for stroke recovery, this approach using fMRI to guide treatment is relatively novel and has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults over 20 years of age * Patients 3 months or more after stroke onset * Patients with NIHSS score of 1 or more to 20 or less * After hearing and fully understanding the detailed explanation of this clinical trial, the subject or legal representative voluntarily decides to participate and agrees in writing to abide by the precautions Exclusion Criteria: Patients who fall under one or more of the following conditions are not eligible to participate in the study. * Patients with systemic infectious disease at the time of participation in the clinical trial * In the case of a person with impaired consent (MMSE less than 10 points), if not accompanied by a guardian * Those with severe medical conditions such as unstable conditions of the cardiovascular system, digestive system, respiratory system, endocrine system, etc., who are in poor general condition * Other cases where the researcher determines that participation in this clinical trial is not appropriate * Those who are contraindicated in repetitive transcranial magnetic stimulation A. When metal materials (deep brain stimulation electrode, brain aneurysm clip, cardiac pacemaker, etc.) are in the body B. Uncontrolled epilepsy (epilepsy), patients with psychiatric disorders * Pregnant, lactating women and patients with potential for pregnancy * Patients with contraindications for imaging tests * Those who have undergone cerebral surgery due to past or current related medical history
Where this trial is running
Seongnam
- Department of Rehabilitation Medicine, CHA Bundang Medical Center — Seongnam, Korea, Republic of (RECRUITING)
Study contacts
- Principal investigator: Kim MinYoung, M.D., Ph.D. — CHA University
- Study coordinator: Kim MinYoung, M.D., Ph.D.
- Email: kmin@cha.ac.kr
- Phone: 82-31-780-6281
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Stroke, Functional Magnetic Resonance Imaging, Repetitive transcranial magnetic stimulation, Rehabilitation