Using magnetic stimulation and training to treat complex regional pain syndrome

The Feasibility of rTMS and Sensorimotor Training Task for the Treatment of Complex Regional Pain Syndrome: A Pilot Study

Not applicable Interventional McMaster University · NCT05197959

This study is testing whether a combination of magnetic brain stimulation and movement training can help reduce pain for people with complex regional pain syndrome.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment18 (estimated)
Ages18 Years to 70 Years
SexAll
SponsorMcMaster University Academic / other
Locations1 site (Hamilton, Ontario)
Trial IDNCT05197959 on ClinicalTrials.gov

What this trial studies

This study investigates the feasibility of using repetitive transcranial magnetic stimulation (rTMS) combined with sensorimotor training to alleviate pain symptoms in patients with complex regional pain syndrome (CRPS). rTMS is a non-invasive technique that delivers magnetic pulses to the brain area controlling movement, while sensorimotor training involves non-invasive nerve stimulation to encourage motor actions. The study aims to assess patient recruitment and adherence to the intervention, as well as the effectiveness of this combined approach in reducing pain symptoms associated with CRPS.

Who should consider this trial

Good fit: Ideal candidates for this study are individuals diagnosed with CRPS type 1 affecting one of their hands.

Not a fit: Patients with a history of moderate to severe chronic pain in other body parts or those with contraindications to transcranial magnetic stimulation may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could provide a new non-invasive treatment option for patients suffering from complex regional pain syndrome.

How similar studies have performed: While the use of rTMS has shown promise in treating various pain conditions, this specific combination of rTMS and sensorimotor training for CRPS is relatively novel and has not been extensively tested.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* A diagnosis of CRPS type 1 affecting one of their hands

Exclusion Criteria:

* A known history of moderate to severe chronic pain in other parts of the body
* Daily use of opioids prior to the CRPS diagnosis
* Contraindications to transcranial magnetic stimulation
* Known psychological diagnosis affecting comprehension
* Inability to participate in the study

Where this trial is running

Hamilton, Ontario

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Complex Regional Pain Syndromerepetitive transcranial magnetic stimulationsensorimotor trainingcomplex regional pain syndrome
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.