Using magnesium to reduce postoperative pain after hip surgery
Magnesium As an Adjuvant Agent for Postoperative Pain Control Following Periacetabular Osteotomy
PHASE4 · University Hospitals Cleveland Medical Center · NCT05947760
This study is testing if giving magnesium during hip surgery can help reduce pain afterward and lower the need for opioid painkillers.
Quick facts
| Phase | PHASE4 |
|---|---|
| Study type | Interventional |
| Enrollment | 64 (estimated) |
| Ages | 14 Years to 89 Years |
| Sex | All |
| Sponsor | University Hospitals Cleveland Medical Center (other) |
| Locations | 1 site (Cleveland, Ohio) |
| Trial ID | NCT05947760 on ClinicalTrials.gov |
What this trial studies
This clinical trial investigates the effectiveness of intravenous magnesium sulfate as an adjuvant treatment during periacetabular osteotomy surgery. The goal is to determine if administering magnesium can lead to decreased postoperative pain and reduce the need for opioid medications. Participants will be monitored for pain levels and opioid usage following their surgery. This phase 4 study aims to provide insights into pain management strategies for patients undergoing this specific surgical procedure.
Who should consider this trial
Good fit: Ideal candidates are patients scheduled for periacetabular osteotomy, with or without hip arthroscopy.
Not a fit: Patients with severe renal insufficiency, heart failure, or certain heart conditions may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly reduce postoperative pain and reliance on opioids for patients undergoing hip surgery.
How similar studies have performed: Other studies have shown promising results with magnesium as a pain management strategy, suggesting potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients undergoing periacetabular osteotomy with or without adjuvant hip arthroscopy Exclusion Criteria: * illiterate or non-English speaking patients * patients with 2nd or 3rd degree AV block * patients with severe renal insufficiency * patients with heart failure * patients with bradycardia
Where this trial is running
Cleveland, Ohio
- University Hospitals — Cleveland, Ohio, United States (RECRUITING)
Study contacts
- Principal investigator: Robert Wetzel, MD — University Hospitals
- Study coordinator: Alex Nighswander
- Email: Alexander.Nighswander@UHhospitals.org
- Phone: 216-844-3190
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Pain, Postoperative, periacetabular osteotomy, IV magnesium sulfate, Decreased opioid usage