Clinical trial Recruiting at 1 site Phase2; Phase3 Interventional Ages 18 and up

Using magnesium sulfate with bupivacaine for pain relief after hip surgery

Official title: Efficacy of Adding Magnesium Sulfate to Bupivacaine in Ultrasound-guided Transmuscular Quadratus Lumborum Block for Postoperative Analgesia in Patients Underdoing Hip Arthroplasty

Run by Tanta University · NCT06956950 · Data updated 2026-11-12

This study is testing if adding magnesium sulfate to a pain relief shot can help adults feel less pain and use fewer opioids after hip surgery.

Quick facts

PhasePhase2; Phase3
Study typeInterventional
Ages18 Years and up
SexAll
Enrollment70 (estimated)
SponsorTanta University
Academic / other
Locations1 site (Tanta, El-Gharbia)
StatusRecruiting
StartedMay 2025
Main results expectedOctober 9, 2025
Study endsNovember 2025
Registry record updatedMay 11, 2025
Trial IDNCT06956950 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults aged 18 and older, classified as ASA class I-III, who are scheduled for hip arthroplasty.

Probably not a fit

Patients with a BMI over 40, allergies to local anesthetics or magnesium sulfate, or severe renal impairment may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial evaluates the effectiveness of adding magnesium sulfate to bupivacaine in an ultrasound-guided transmuscular quadratus lumborum block for postoperative pain management in adults undergoing hip arthroplasty. The study aims to determine if magnesium sulfate can reduce pain scores and total opioid consumption compared to a placebo. Participants will receive either the combination of magnesium sulfate and bupivacaine or bupivacaine with saline, followed by monitoring for pain and side effects for 48 hours post-surgery.

Why it matters

Potential benefit: If successful, this approach could lead to improved pain management and reduced opioid use after hip arthroplasty.

How similar studies have gone: Previous studies have shown promising results with the addition of magnesium sulfate in regional anesthesia techniques, suggesting potential efficacy in this approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age ≥ 18 years.
* American Society of Anesthesiology (ASA) class I-III
* Undergoing hip arthroplasty .

Exclusion Criteria:

* Patient refusal.
* Body mass index (BMI) \> 40 Kg/m2.
* Allergy to local anesthetics or magnesium sulphate.
* coexisting coagulopathy.
* Local infection at puncture site.
* Severe renal impairment ( eGFR \< 30 ml/min)

Where it's running

  • Faculty of medicine
    Tanta, El-Gharbia, Egypt
    Recruiting

Study contacts

  • Principal investigator: Mostafa Mohammad Abdelsattar Elbagoury, MD — lecturer of anesthesia and surgical ICU and pain medicine
  • Study coordinator: Mostafa Mohammad Abdelsattar Elbagoury, MD
  • Email: mostafa.elbagoury@med.tanta.edu.eg
  • Phone: +201116297741

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
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Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.