Using magnesium sulfate with bupivacaine for pain relief after hip surgery
Official title: Efficacy of Adding Magnesium Sulfate to Bupivacaine in Ultrasound-guided Transmuscular Quadratus Lumborum Block for Postoperative Analgesia in Patients Underdoing Hip Arthroplasty
Run by Tanta University · NCT06956950 · Data updated 2026-11-12
This study is testing if adding magnesium sulfate to a pain relief shot can help adults feel less pain and use fewer opioids after hip surgery.
Quick facts
| Phase | Phase2; Phase3 |
|---|---|
| Study type | Interventional |
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 70 (estimated) |
| Sponsor | Tanta University Academic / other |
| Locations | 1 site (Tanta, El-Gharbia) |
| Status | Recruiting |
| Started | May 2025 |
| Main results expected | October 9, 2025 |
| Study ends | November 2025 |
| Registry record updated | May 11, 2025 |
| Trial ID | NCT06956950 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults aged 18 and older, classified as ASA class I-III, who are scheduled for hip arthroplasty.
✕Probably not a fit
Patients with a BMI over 40, allergies to local anesthetics or magnesium sulfate, or severe renal impairment may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This clinical trial evaluates the effectiveness of adding magnesium sulfate to bupivacaine in an ultrasound-guided transmuscular quadratus lumborum block for postoperative pain management in adults undergoing hip arthroplasty. The study aims to determine if magnesium sulfate can reduce pain scores and total opioid consumption compared to a placebo. Participants will receive either the combination of magnesium sulfate and bupivacaine or bupivacaine with saline, followed by monitoring for pain and side effects for 48 hours post-surgery.
Why it matters
Potential benefit: If successful, this approach could lead to improved pain management and reduced opioid use after hip arthroplasty.
How similar studies have gone: Previous studies have shown promising results with the addition of magnesium sulfate in regional anesthesia techniques, suggesting potential efficacy in this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age ≥ 18 years. * American Society of Anesthesiology (ASA) class I-III * Undergoing hip arthroplasty . Exclusion Criteria: * Patient refusal. * Body mass index (BMI) \> 40 Kg/m2. * Allergy to local anesthetics or magnesium sulphate. * coexisting coagulopathy. * Local infection at puncture site. * Severe renal impairment ( eGFR \< 30 ml/min)
Where it's running
-
Faculty of medicine
Tanta, El-Gharbia, Egypt Recruiting
Study contacts
- Principal investigator: Mostafa Mohammad Abdelsattar Elbagoury, MD — lecturer of anesthesia and surgical ICU and pain medicine
- Study coordinator: Mostafa Mohammad Abdelsattar Elbagoury, MD
- Email: mostafa.elbagoury@med.tanta.edu.eg
- Phone: +201116297741
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.