Clinical trial Recruiting at 1 site Observational Ages 18 and up

Using machine learning to improve early diagnosis of acute cardiovascular conditions

Official title: MAchine Learning to Boost the Early Diagnosis of Acute Cardiovascular Conditions

Run by University Hospital, Basel, Switzerland · NCT06927791 · Data updated 2026-11-12

This study is testing a new tool that uses advanced computer technology to help doctors quickly and accurately diagnose serious heart problems in patients who come to the emergency room with chest pain or trouble breathing.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment200000 (estimated)
SponsorUniversity Hospital, Basel, Switzerland
Academic / other
Locations1 site (Basel)
StatusRecruiting
StartedApril 1, 2024
Main results expectedMarch 2027
Study endsMarch 2027
Registry record updatedApril 15, 2025
Trial IDNCT06927791 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are patients presenting with symptoms of acute cardiovascular disease, such as chest pain or dyspnea.

Probably not a fit

Patients under 18 years old, those in cardiogenic shock, or individuals with chronic terminal kidney failure requiring dialysis may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This project aims to develop a clinical decision support tool that integrates established diagnostic variables with machine learning models to enhance the rapid diagnosis of acute cardiovascular diseases in emergency department patients presenting with chest pain or dyspnea. By utilizing advanced techniques such as deep transfer learning and automated machine learning, the study seeks to improve diagnostic accuracy, expedite patient management, and minimize medical errors. The research builds on previous large-scale studies in cardiovascular biomarker research and precision medicine, addressing the challenges of diagnosing life-threatening conditions in a timely manner.

Why it matters

Potential benefit: If successful, this approach could significantly improve the speed and accuracy of diagnosing acute cardiovascular conditions, potentially saving lives.

How similar studies have gone: Other studies have shown promise in using machine learning for diagnostic purposes in cardiovascular conditions, indicating a potential for success in this novel approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

• Acute cardiovascular disease (ACVD)

Exclusion Criteria

* age \< 18 years old
* patients presenting in cardiogenic shock
* chronic terminal kidney failure requiring dialysis

Where it's running

  • University Hospital Basel
    Basel, Switzerland
    Recruiting

Study contacts

  • Principal investigator: Jasper Boeddinghaus, PD Dr. med. — University Hospital, Basel, Switzerland
  • Study coordinator: Jasper Boeddinghaus, PD Dr. med.
  • Email: jasper.boeddinghaus@usb.ch
  • Phone: +41 61 32 87897

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.