Using machine learning to improve early diagnosis of acute cardiovascular conditions
Official title: MAchine Learning to Boost the Early Diagnosis of Acute Cardiovascular Conditions
Run by University Hospital, Basel, Switzerland · NCT06927791 · Data updated 2026-11-12
This study is testing a new tool that uses advanced computer technology to help doctors quickly and accurately diagnose serious heart problems in patients who come to the emergency room with chest pain or trouble breathing.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 200000 (estimated) |
| Sponsor | University Hospital, Basel, Switzerland Academic / other |
| Locations | 1 site (Basel) |
| Status | Recruiting |
| Started | April 1, 2024 |
| Main results expected | March 2027 |
| Study ends | March 2027 |
| Registry record updated | April 15, 2025 |
| Trial ID | NCT06927791 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are patients presenting with symptoms of acute cardiovascular disease, such as chest pain or dyspnea.
✕Probably not a fit
Patients under 18 years old, those in cardiogenic shock, or individuals with chronic terminal kidney failure requiring dialysis may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This project aims to develop a clinical decision support tool that integrates established diagnostic variables with machine learning models to enhance the rapid diagnosis of acute cardiovascular diseases in emergency department patients presenting with chest pain or dyspnea. By utilizing advanced techniques such as deep transfer learning and automated machine learning, the study seeks to improve diagnostic accuracy, expedite patient management, and minimize medical errors. The research builds on previous large-scale studies in cardiovascular biomarker research and precision medicine, addressing the challenges of diagnosing life-threatening conditions in a timely manner.
Why it matters
Potential benefit: If successful, this approach could significantly improve the speed and accuracy of diagnosing acute cardiovascular conditions, potentially saving lives.
How similar studies have gone: Other studies have shown promise in using machine learning for diagnostic purposes in cardiovascular conditions, indicating a potential for success in this novel approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: • Acute cardiovascular disease (ACVD) Exclusion Criteria * age \< 18 years old * patients presenting in cardiogenic shock * chronic terminal kidney failure requiring dialysis
Where it's running
-
University Hospital Basel
Basel, Switzerland Recruiting
Study contacts
- Principal investigator: Jasper Boeddinghaus, PD Dr. med. — University Hospital, Basel, Switzerland
- Study coordinator: Jasper Boeddinghaus, PD Dr. med.
- Email: jasper.boeddinghaus@usb.ch
- Phone: +41 61 32 87897
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.