Using lung ultrasound to guide respiratory therapy in neonates
Neonatologist-performed Lung Ultrasound (NPLUS) to Guide Respiratory Therapy to Prevent Extubation Failure in Term and Preterm Neonates- a Randomized Controlled Pilot Trial
NA · Medical University of Graz · NCT06469580
This study tests if using lung ultrasound can help doctors provide better respiratory care for newborns after they stop using breathing machines.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 40 (estimated) |
| Ages | 1 Minute to 6 Months |
| Sex | All |
| Sponsor | Medical University of Graz (other) |
| Locations | 1 site (Graz, Styria) |
| Trial ID | NCT06469580 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effectiveness of neonatologist-performed lung ultrasound (NPLUS) in guiding respiratory therapy for neonates after they are weaned from invasive mechanical ventilation. The goal is to assess the diagnostic accuracy of lung ultrasound and determine if it can help prevent extubation failure by allowing for timely interventions before clinical deterioration occurs. The study utilizes point-of-care ultrasound to provide immediate bedside evaluations, which can lead to better management of respiratory conditions in neonates.
Who should consider this trial
Good fit: Ideal candidates for this study are preterm and full-term neonates who are currently receiving invasive mechanical ventilation.
Not a fit: Patients who are not receiving invasive mechanical ventilation or those who cannot provide informed consent will not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly reduce the rates of extubation failure in neonates, leading to improved respiratory outcomes.
How similar studies have performed: Other studies have shown promising results with lung ultrasound in assessing neonatal respiratory conditions, indicating that this approach is supported by prior research.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * All preterm and full-term neonates receiving invasive mechanical ventilation at the Division of Neonatology of the Medical University of Graz AND * Written informed consent was obtained from parents prior to extubation Exclusion Criteria: none
Where this trial is running
Graz, Styria
- Department of Pediatrics, Division of Neonatology, Medical University of Graz — Graz, Styria, Austria (RECRUITING)
Study contacts
- Principal investigator: Bernhard Schwaberger, MD PhD — Division of Neonatology, Medical University of Graz, Austria
- Study coordinator: Bernhard Schwaberger, MD PhD
- Email: bernhard.schwaberger@medunigraz.at
- Phone: +4331638530018
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Neonatal Disease, neonatologist performed lung ultrasound, extubation failure, neonates, consolidation