Clinical trial Recruiting at 1 site Interventional Ages 18 to 70

Using low-thoracic epidural anesthesia for kidney removal surgery.

Official title: Low-Thoracic Epidural Anesthesia For Laparoscopic Nephrectomy In Adult Patients.

Run by Cairo University · NCT04546230 · Data updated 2026-11-12

This study is testing if using low-thoracic epidural anesthesia during kidney removal surgery can help older and high-risk patients recover better and feel more satisfied compared to general anesthesia.

Quick facts

Study typeInterventional
Ages18 Years to 70 Years
SexAll
Enrollment80 (estimated)
SponsorCairo University
Academic / other
Locations1 site (Cairo)
StatusRecruiting
StartedSeptember 19, 2020
Main results expectedDecember 2026
Study endsDecember 2026
Registry record updatedJanuary 12, 2026
Trial IDNCT04546230 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adult patients classified as ASA I-II who are scheduled for laparoscopic nephrectomy.

Probably not a fit

Patients who refuse participation or have contraindications to regional anesthesia, such as coagulopathy or allergies to local anesthetics, may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study compares the effectiveness of low-thoracic epidural anesthesia to general anesthesia in patients undergoing laparoscopic nephrectomy, a minimally invasive kidney removal procedure. The research focuses on older and high-risk patients, aiming to enhance patient satisfaction and reduce complications associated with general anesthesia. By utilizing a modified lateral decubitus position and low-pressure pneumoperitoneum, the study seeks to evaluate the benefits of regional anesthesia in terms of post-operative recovery and overall outcomes.

Why it matters

Potential benefit: If successful, this approach could lead to improved recovery experiences and reduced complications for patients undergoing laparoscopic nephrectomy.

How similar studies have gone: Other studies have shown promising results with regional anesthesia techniques in similar surgical contexts, suggesting potential for success in this approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* ASA I - II.
* Adult patients scheduled for laparoscopic nephrectomy.

Exclusion Criteria:

* Patient refusal.
* Contraindication to regional anesthesia (e.g., coagulopathy, site infection).
* Allergy to local anesthetics.

Where it's running

  • Cairo University Hospitals
    Cairo, Egypt
    Recruiting

Study contacts

  • Principal investigator: Nazmy S Michael, MD — Kasr Al-Ainy Hospital, Faculty of Medicine, Cairo University
  • Study coordinator: Nazmy S Michael, MD
  • Email: nazmy.seif@gmail.com
  • Phone: 01227400808

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.