Using low-thoracic epidural anesthesia for kidney removal surgery.
Official title: Low-Thoracic Epidural Anesthesia For Laparoscopic Nephrectomy In Adult Patients.
Run by Cairo University · NCT04546230 · Data updated 2026-11-12
This study is testing if using low-thoracic epidural anesthesia during kidney removal surgery can help older and high-risk patients recover better and feel more satisfied compared to general anesthesia.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 70 Years |
| Sex | All |
| Enrollment | 80 (estimated) |
| Sponsor | Cairo University Academic / other |
| Locations | 1 site (Cairo) |
| Status | Recruiting |
| Started | September 19, 2020 |
| Main results expected | December 2026 |
| Study ends | December 2026 |
| Registry record updated | January 12, 2026 |
| Trial ID | NCT04546230 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adult patients classified as ASA I-II who are scheduled for laparoscopic nephrectomy.
✕Probably not a fit
Patients who refuse participation or have contraindications to regional anesthesia, such as coagulopathy or allergies to local anesthetics, may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study compares the effectiveness of low-thoracic epidural anesthesia to general anesthesia in patients undergoing laparoscopic nephrectomy, a minimally invasive kidney removal procedure. The research focuses on older and high-risk patients, aiming to enhance patient satisfaction and reduce complications associated with general anesthesia. By utilizing a modified lateral decubitus position and low-pressure pneumoperitoneum, the study seeks to evaluate the benefits of regional anesthesia in terms of post-operative recovery and overall outcomes.
Why it matters
Potential benefit: If successful, this approach could lead to improved recovery experiences and reduced complications for patients undergoing laparoscopic nephrectomy.
How similar studies have gone: Other studies have shown promising results with regional anesthesia techniques in similar surgical contexts, suggesting potential for success in this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * ASA I - II. * Adult patients scheduled for laparoscopic nephrectomy. Exclusion Criteria: * Patient refusal. * Contraindication to regional anesthesia (e.g., coagulopathy, site infection). * Allergy to local anesthetics.
Where it's running
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Cairo University Hospitals
Cairo, Egypt Recruiting
Study contacts
- Principal investigator: Nazmy S Michael, MD — Kasr Al-Ainy Hospital, Faculty of Medicine, Cairo University
- Study coordinator: Nazmy S Michael, MD
- Email: nazmy.seif@gmail.com
- Phone: 01227400808
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Recovery, quality of life, and physical function after partial or radical nephrectomy
This study tests recovery, quality of life, and physical function before and after nephrectomy to see how patients fare depending on the surgery type.
-
Pain management plan implementation for major open abdominal surgeries
This trial tests an opioid-epidural pain management approach to see if it improves post-surgical pain control for adults undergoing open abdominal procedures like colectomy, hepatectomy, and nephrectomy.
-
ESP vs EXORA blocks after laparoscopic nephrectomy
This observational study compares two pain-control blocks (ESP and EXORA) used after laparoscopic kidney removal to see which provides better pain relief and recovery.
-
Laparoscopy vs Open Surgery for Endometrial Cancer Staging in Low-Resource Settings
This study tests whether laparoscopic surgical staging for early endometrial cancer leads to faster first ambulation compared with open surgery in low-resource settings.
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Contrast-enhanced ultrasound and super-resolution imaging to predict kidney function after nephrectomy
This project will test whether special ultrasound scans—contrast-enhanced ultrasound and super-resolution imaging—can help predict kidney function and the risk and recovery of acute kidney injury in adults having partial or radical nephrectomy for kidney cancer.
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New kidney biomarkers to predict kidney injury after radical nephrectomy
We will test whether measuring new kidney biomarkers before, during, and after radical nephrectomy can help predict acute kidney injury and one-year chronic kidney disease in adults having the operation.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.