Using low-intensity laser to improve smell and taste loss after COVID-19
Efficacy of Photobiomodulation in the Rehabilitation of Olfactory Dysfunctions Induced by Long COVID-19
This study is testing whether low-intensity laser treatment can help people who have lost their sense of smell and taste for more than six months after having COVID-19.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 30 (estimated) |
| Ages | 18 Years to 70 Years |
| Sex | All |
| Sponsor | Gaffree & Guinle Universitary Hospital Academic / other |
| Locations | 1 site (Rio de Janeiro) |
| Trial ID | NCT06423495 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effectiveness of low-intensity laser treatment for individuals experiencing loss of smell and taste due to COVID-19 infection. It will involve 30 participants who have reported these symptoms for more than six months post-infection. Participants will receive laser therapy at the Gafree Guinle University Hospital, and their progress will be monitored to assess improvements in chemosensory functions. The study aims to identify which specific changes yield the best results from the treatment.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 and older who have experienced loss of smell and taste for more than six months following a confirmed COVID-19 infection.
Not a fit: Patients with pre-existing comorbidities affecting smell and taste, or those with a history of head and neck cancer, will not benefit from this study.
Why it matters
Potential benefit: If successful, this treatment could significantly improve the quality of life for patients suffering from long-term olfactory and gustatory dysfunctions after COVID-19.
How similar studies have performed: While there is limited research on the use of low-intensity laser for this specific purpose, similar approaches have shown promise in treating other sensory dysfunctions.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients who complained of loss of smell and taste more than 6 months after COVID-19 infection, aged 18 years or older, with proof of infection by PCR, will be included in the study. Exclusion Criteria: * Patients with comorbidities prior to COVID-19 infection that could interfere with the functions of smell and taste will be excluded from the study; patients with a history of head and neck cancer, epileptic patients; mouth breathing patients; and pregnant women.
Where this trial is running
Rio de Janeiro
- university hospital Gafree Guinle — Rio de Janeiro, Brazil (Recruiting)
Study contacts
- Principal investigator: Deborah Santos Sales, Phd — University hospital Gafree Guinle - UNIRIO
- Study coordinator: DEBORAH S SALES, phd
- Email: deborahsales.fono@gmail.com
- Phone: +5521982161520
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.