Using low dose injectable progesterone to trigger ovulation
Role of Low Dose Injectable Progesterone in Triggering Ovulation: A Randomized Controlled Trial
NA · The General Authority for Teaching Hospitals and Institutes · NCT06928844
This study is testing whether a low dose of injectable progesterone can help women aged 20 to 35 with unexplained infertility to ovulate better than a placebo.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 120 (estimated) |
| Ages | 20 Years to 35 Years |
| Sex | Female |
| Sponsor | The General Authority for Teaching Hospitals and Institutes (network) |
| Locations | 1 site (Cairo) |
| Trial ID | NCT06928844 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effectiveness of low dose injectable progesterone in triggering ovulation in women experiencing infertility. It focuses on women aged 20 to 35 with unexplained infertility and normal basal follicle-stimulating hormone levels. The study compares the outcomes of progesterone treatment against a placebo to determine its impact on ovulation induction. The research aims to provide insights into alternative methods for enhancing fertility in women undergoing assisted reproductive technologies.
Who should consider this trial
Good fit: Ideal candidates for this study are infertile women aged 20 to 35 with normal basal FSH levels.
Not a fit: Patients with poor ovarian reserve, immunological diseases, endometriosis, uterine abnormalities, high BMI, or abnormal endometrial thickness may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could offer a new, effective treatment option for women struggling with unexplained infertility.
How similar studies have performed: While the use of progesterone in fertility treatments is established, this specific approach of low dose injectable progesterone for triggering ovulation is relatively novel and has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age from 20 to 35 years. * Infertile women. * Basal follicle-stimulating hormone (FSH) level \<10 mIU/ml. Exclusion Criteria: * Poor ovarian reserve. * Immunological disease. * Endometriosis. * Uterine abnormality. * Body mass index (BMI) \>30 kg/m2. * Endometrial thickness \<8 or \>12 mm on the day of triggering.
Where this trial is running
Cairo
- Teaching Hospitals and Institutes — Cairo, Egypt (RECRUITING)
Study contacts
- Study coordinator: Abeer A El Shabasi, MD
- Email: abear.elshabacy@gmail.com
- Phone: 00201223331182
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Low Dose, Progesterone, Triggering Ovulation