Using long intravenous catheters for antimicrobial therapy

Long Peripheral Intravenous Catheter Insertion Site and Catheter-related Complications in Antimicrobial Therapy: a Randomized Controlled Trial

NA · Sir Run Run Shaw Hospital · NCT06455228

This study tests whether using long intravenous catheters in different places on the body can make it safer and more comfortable for patients getting long-term antimicrobial treatment.

Quick facts

PhaseNA
Study typeInterventional
Enrollment90 (estimated)
Ages18 Years and up
SexAll
SponsorSir Run Run Shaw Hospital (other)
Locations1 site (Hangzhou)
Trial IDNCT06455228 on ClinicalTrials.gov

What this trial studies

This study investigates the use of long peripheral intravenous catheters (PIVCs) in patients receiving antimicrobial therapy, focusing on the effects of different insertion sites. The goal is to identify the optimal placement site that minimizes complications, extends catheter retention time, and reduces patient discomfort. By comparing outcomes based on various insertion locations, the study aims to provide evidence-based recommendations for clinicians. The research is particularly relevant for patients requiring prolonged intravenous treatment.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18 and older who require intravenous antimicrobial therapy for at least one week during hospitalization.

Not a fit: Patients with a history of complications at the catheterization site or those planning to be discharged with a catheter may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved patient comfort and reduced complications associated with long-term intravenous antimicrobial therapy.

How similar studies have performed: While there may be studies on catheter placement, this specific approach focusing on long PIVCs in antimicrobial therapy is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* ① estimated time of intravenous infusion ≥1 week; ② age: ≥18 years; ③ antimicrobial therapy was only used for treatment during hospitalization, with a pH value of 5-9 and osmotic pressure \< 900 mOsm/L; and ④ patients were conscious and able to communicate normally; ⑤ the catheter-to-vessel ratio is less than 45%.

Exclusion Criteria:

* ① a history of radiotherapy, thrombosis, and trauma at the catheterization site and ② plans to discharge with a catheter during the study duration.

Where this trial is running

Hangzhou

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Antimicrobial

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.