Using light therapy to improve dental plaque control at home

Photodynamic Treatment in the Management of Residual Biofilm - a Crossover Study

Not applicable Interventional Koite Health Oy · NCT06860321

This study is testing whether a new light therapy device can help people do a better job at controlling dental plaque at home compared to regular brushing and flossing.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment20 (estimated)
Ages18 Years and up
SexAll
SponsorKoite Health Oy Industry-sponsored
Locations1 site (Helsinki)
Trial IDNCT06860321 on ClinicalTrials.gov

What this trial studies

This study investigates the effectiveness of a home-use dual-light antibacterial device in reducing residual biofilm compared to traditional mechanical cleaning methods. Participants will be randomly assigned to use either the dual-light device or standard oral care techniques in a crossover design. The device utilizes a photosensitive molecule activated by light to generate reactive oxygen species that target bacteria. The study aims to enhance dental hygiene practices and improve outcomes for plaque control.

Who should consider this trial

Good fit: Ideal candidates are healthy adults who can perform regular oral self-care.

Not a fit: Patients with periodontitis or those unable to maintain regular oral hygiene may not benefit from this study.

Why it matters

Potential benefit: If successful, this treatment could significantly improve dental hygiene and reduce plaque buildup for patients.

How similar studies have performed: Previous studies have shown positive outcomes with photodynamic therapy in dental applications, suggesting potential success for this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Signed informed consent voluntarily
* Good general health

Exclusion Criteria:

* Periodontitis
* Inability to perform regular oral self-care

Where this trial is running

Helsinki

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Healthy AdultsPlaque, DentalaPDTphotodynamic treatmentplaque control
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.